DICP OpenIR
Development of phosphopeptide enrichment techniques for phosphoproteome analysis
Han, Guanghui; Ye, Mingliang; Zou, Hanfa; Zou HF(邹汉法); Zou HF(邹汉法)
刊名ANALYST
2008-09-01
ISSN0003-2654
DOI10.1039/b806775a
133期:9页:1128-1138
收录类别SCI
文章类型Review
部门归属18
项目归属1809
产权排名1;1
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]SITE-DIRECTED MUTAGENESIS ; MALDI-TOF-MS ; KINASE-SPECIFIC PHOSPHORYLATION ; IONIZATION MASS-SPECTROMETRY ; ION AFFINITY-CHROMATOGRAPHY ; CORE-SHELL MICROSPHERES ; HIGHLY SPECIFIC CAPTURE ; MONOLITHIC CAPILLARY COLUMN ; PHOSPHOAMINO ACID ANALYSIS ; IMMOBILIZED METAL-IONS
英文摘要Protein phosphorylation is one of the most biologically relevant and ubiquitous post-translational modifications. The analysis of protein phosphorylation is very challenging due to its highly dynamic nature and low stoichiometry. In this article, recent techniques developed for phosphoproteome analysis are reviewed with an emphasis on the new developments in this field in China. To improve the performance of phosphoproteome analysis, many novel methods, either by application of new separation mechanisms or by adoption of new separation materials, were developed to specifically enrich phosphopeptides from complex protein digests. A series of new materials, including nanostructure materials, magnetic materials, and monolithic materials, were applied to prepare immobilized affinity chromatography or metal oxide affinity chromatography to improve the performance of phosphopeptide enrichment. Besides, new software tools were also developed to validate phosphopeptide identification and predict kinase specific phosphorylation sites.
语种英语
原文出处查看原文
WOS记录号WOS:000259449400002
引用统计
被引频次:89[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/100173
专题中国科学院大连化学物理研究所
通讯作者Zou HF(邹汉法); Zou HF(邹汉法)
作者单位Chinese Acad Sci, Natl Chromatog R&A Ctr, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Han, Guanghui,Ye, Mingliang,Zou, Hanfa,et al. Development of phosphopeptide enrichment techniques for phosphoproteome analysis[J]. ANALYST,2008,133(9):1128-1138.
APA Han, Guanghui,Ye, Mingliang,Zou, Hanfa,邹汉法,&邹汉法.(2008).Development of phosphopeptide enrichment techniques for phosphoproteome analysis.ANALYST,133(9),1128-1138.
MLA Han, Guanghui,et al."Development of phosphopeptide enrichment techniques for phosphoproteome analysis".ANALYST 133.9(2008):1128-1138.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Han, Guanghui]的文章
[Ye, Mingliang]的文章
[Zou, Hanfa]的文章
百度学术
百度学术中相似的文章
[Han, Guanghui]的文章
[Ye, Mingliang]的文章
[Zou, Hanfa]的文章
必应学术
必应学术中相似的文章
[Han, Guanghui]的文章
[Ye, Mingliang]的文章
[Zou, Hanfa]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。