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Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry
Zhou, Da-Yong1; Xing, Rong2; Xu, Qing1; Xue, Xing-Ya1; Zhang, Fei-Fang1; Liang, Xin-Miao1; Liang XM(梁鑫淼); Liang XM(梁鑫淼)
关键词Lc-msn Polymethoxylated Flavones Fructus Aurantii Rat Metabolism
刊名JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2008-02-13
DOI10.1016/j.jpba.2007.11.019
46期:3页:543-549
收录类别SCI
文章类型Article
部门归属18
项目归属1803
产权排名1;1
WOS标题词Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine
类目[WOS]Chemistry, Analytical ; Pharmacology & Pharmacy
研究领域[WOS]Chemistry ; Pharmacology & Pharmacy
关键词[WOS]CELL-LINES ; NOBILETIN ; BIOTRANSFORMATION ; IDENTIFICATION ; ABSORPTION ; HAMSTERS ; URINE ; ARRAY ; PEEL
英文摘要A LC with full scan MSn method was developed in order to investigate the in vivo absorption and biotransformation of polymethoxylated flavones (PMFs) by analysis of plasma samples from rats after ingestion of Fructus aurantii extract. Four parent compounds and six metabolites with intact flavonoid structures were tentatively identified. The metabolites were either glucuronides of parent compounds or glucuronides of demethylated products of parent compounds. (c) 2007 Elsevier B.V. All rights reserved.
语种英语
原文出处查看原文
WOS记录号WOS:000253100400016
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/100193
专题中国科学院大连化学物理研究所
通讯作者Liang XM(梁鑫淼); Liang XM(梁鑫淼)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Dalinan Med Univ, Dept Pathol Physiol, Dalian 116023, Peoples R China
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Zhou, Da-Yong,Xing, Rong,Xu, Qing,et al. Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2008,46(3):543-549.
APA Zhou, Da-Yong.,Xing, Rong.,Xu, Qing.,Xue, Xing-Ya.,Zhang, Fei-Fang.,...&梁鑫淼.(2008).Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,46(3),543-549.
MLA Zhou, Da-Yong,et al."Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 46.3(2008):543-549.
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