DICP OpenIR
Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry
Ma, Chenfei1; Wang, Huahong2; Lu, Xin1; Xu, Guowang1; Liu, Benye2; Xu GW(许国旺)
关键词Artemisia Annua L. Metabolic Fingerprinting Metabolomics Pattern Recognition Developmental Stage
刊名JOURNAL OF CHROMATOGRAPHY A
2008-04-04
DOI10.1016/j.chroma.2007.09.023
1186期:1-2页:412-419
收录类别SCI
文章类型Article
部门归属18
项目归属1808
产权排名1;1
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]PERFORMANCE LIQUID-CHROMATOGRAPHY ; DIHYDROARTEMISINIC ACID ; BIOSYNTHETIC PRECURSORS ; IDENTIFICATION ; H-1-NMR ; PLANTS
英文摘要Artemisia annua L. is an annual herb native of Asia and this plant has been famous for the discovery of the anti-malarial drug artemisinin since 1971. In this work, to investigate variety of whole metabolites, metabolic fingerprinting analysis of A. annua L. was carried out by GC and GC-MS coupled with trimethylsilyl derivatisation. Principal component analysis and partial least squares discriminant analysis were employed to classify GC data of A. annua L. samples at five developmental stages. The results indicated that there was no distinct difference of metabolites between control (001) and transgenic strain (F4) from the tender seedling stage to adult seedling stage, but clear differences were detected at pre-flower budding stage, flower budding stage and full flowering stage. Three precursors of artemisinin biosynthesis were studied at five developmental stages and found that a possible bottleneck exists in the conversion from artemisinic acid or dihydroartemisinic acid to artemisinin. (C) 2007 Elsevier B.V. All rights reserved.
语种英语
原文出处查看原文
WOS记录号WOS:000254884700036
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/100431
专题中国科学院大连化学物理研究所
通讯作者Xu GW(许国旺)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatograph R&A Ctr, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Inst Bot, Beijing 100093, Peoples R China
推荐引用方式
GB/T 7714
Ma, Chenfei,Wang, Huahong,Lu, Xin,et al. Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry[J]. JOURNAL OF CHROMATOGRAPHY A,2008,1186(1-2):412-419.
APA Ma, Chenfei,Wang, Huahong,Lu, Xin,Xu, Guowang,Liu, Benye,&许国旺.(2008).Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry.JOURNAL OF CHROMATOGRAPHY A,1186(1-2),412-419.
MLA Ma, Chenfei,et al."Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry".JOURNAL OF CHROMATOGRAPHY A 1186.1-2(2008):412-419.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Ma, Chenfei]的文章
[Wang, Huahong]的文章
[Lu, Xin]的文章
百度学术
百度学术中相似的文章
[Ma, Chenfei]的文章
[Wang, Huahong]的文章
[Lu, Xin]的文章
必应学术
必应学术中相似的文章
[Ma, Chenfei]的文章
[Wang, Huahong]的文章
[Lu, Xin]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。