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The JMJD2 members of histone demethylase revisited
Tan, Haidong; Wu, Siguo; Wang, Jinxia; Zhao, Zongbao (Kent); Tan HD(谭海东)
关键词Eukaryotes Histone Demethylation In Vivo Study Jmjd2 Prokaryotes Protein-protein Interaction
刊名MOLECULAR BIOLOGY REPORTS
2008-12-01
DOI10.1007/s11033-007-9121-3
35期:4页:551-556
收录类别SCI
文章类型Article
部门归属18
项目归属1816
产权排名1;1
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biochemistry & Molecular Biology
研究领域[WOS]Biochemistry & Molecular Biology
关键词[WOS]ANDROGEN-RECEPTOR ; FUNCTIONAL-CHARACTERIZATION ; S-ADENOSYLMETHIONINE ; MAMMALIAN-CELLS ; METHYL GROUPS ; H3 ; PROTEIN ; FAMILY ; LSD1 ; TRANSCRIPTION
英文摘要The study of histone lysine demethylases has become very hot recently. Many histone demethylases have been reported by different research groups with various techniques. However, how many histone lysine-methylation states can be removed by one specific demethylase and how many demethylases can remove one specific histone lysine-methylation state? It remains a daunting challenge to answer these questions to date. An in-depth discussion on recent results, three important points were provided: (1) Some demethylases can remove more histone lysine-methylation states; (2) Some prokaryotes might be endowed with histone lysine demethylases although they are devoid of histones; (3) Protein-protein interaction provides a valuable framework for a better understanding of the functions of the histone lysine demethylases. All of these will be beneficial to a better understanding of demethylases and suggest how future research can be improved.
语种英语
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WOS记录号WOS:000261424100010
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被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/101159
专题中国科学院大连化学物理研究所
通讯作者Tan HD(谭海东)
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
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Tan, Haidong,Wu, Siguo,Wang, Jinxia,et al. The JMJD2 members of histone demethylase revisited[J]. MOLECULAR BIOLOGY REPORTS,2008,35(4):551-556.
APA Tan, Haidong,Wu, Siguo,Wang, Jinxia,Zhao, Zongbao ,&谭海东.(2008).The JMJD2 members of histone demethylase revisited.MOLECULAR BIOLOGY REPORTS,35(4),551-556.
MLA Tan, Haidong,et al."The JMJD2 members of histone demethylase revisited".MOLECULAR BIOLOGY REPORTS 35.4(2008):551-556.
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