DICP OpenIR
Prediction of retention times and peak shape parameters of unknown compounds in traditional Chinese medicine under gradient conditions by ultra performance liquid chromatography
Jin, Gaowa; Xue, Xingya; Zhang, Feifang; Zhang, Xiuli; Xu, Qing; Jin, Yu; Liang, Xinmiao; Liang XM(梁鑫淼)
关键词Prediction Retention Time Peak Shape Parameter Peak Recognition Traditional Chinese Medicine Ultra Performance Liquid Chromatography
刊名ANALYTICA CHIMICA ACTA
2008-10-17
DOI10.1016/j.aca.2008.08.044
628期:1页:95-103
收录类别SCI
文章类型Article
部门归属18
项目归属1803
产权排名1;1
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]RESTRICTED MULTIPARAMETER APPROACH ; FLIGHT MASS-SPECTROMETRY ; MODIFIED GAUSSIAN MODEL ; COMPUTER-SIMULATION ; PRIORITY PESTICIDES ; GAS-CHROMATOGRAPHY ; SOLVENT-STRENGTH ; OPTIMIZATION ; THROUGHPUT ; ELUTION
英文摘要A method for the prediction of retention times and peak shape parameters of compounds of unknown structures in complex sample under linear gradient mobile phase conditions was established. Taking traditional Chinese medicine (TCM)-Rhizoma Corydalis as an example, the chromatographic retention parameters and peak shape parameters of 24 compounds were studied. After recognition of each peak under five different linear gradient conditions, the binary parameters equation was established to calculate the retention parameters on ultra performance liquid chromatography (UPLC) with 2.1 mm i.d. column packed with 1.7 mu m particles. And further retention times under other binary gradient conditions were predicted. The largest relative error of predicted retention time for each compound in R. Corydalis was 0.75%. The exponentially modified Gaussian (EMG) model and automatic peak curve-fitting method were used to resolve the overlapping peaks, to calculate the peak shape parameters and to obtain the peak shape rules. The peak shape parameters sigma, tau and W(h/2) possessed the linear relationship with the equivalent retention time t(R)(*). Based on peak shape rules, peak shape parameters under other mobile phase conditions were predicted. The predicted peak shape parameters were coincident with the experimental results. (C) 2008 Elsevier B.V All rights reserved.
语种英语
原文出处查看原文
WOS记录号WOS:000261760700012
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/101371
专题中国科学院大连化学物理研究所
通讯作者Liang XM(梁鑫淼)
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Jin, Gaowa,Xue, Xingya,Zhang, Feifang,et al. Prediction of retention times and peak shape parameters of unknown compounds in traditional Chinese medicine under gradient conditions by ultra performance liquid chromatography[J]. ANALYTICA CHIMICA ACTA,2008,628(1):95-103.
APA Jin, Gaowa.,Xue, Xingya.,Zhang, Feifang.,Zhang, Xiuli.,Xu, Qing.,...&梁鑫淼.(2008).Prediction of retention times and peak shape parameters of unknown compounds in traditional Chinese medicine under gradient conditions by ultra performance liquid chromatography.ANALYTICA CHIMICA ACTA,628(1),95-103.
MLA Jin, Gaowa,et al."Prediction of retention times and peak shape parameters of unknown compounds in traditional Chinese medicine under gradient conditions by ultra performance liquid chromatography".ANALYTICA CHIMICA ACTA 628.1(2008):95-103.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Jin, Gaowa]的文章
[Xue, Xingya]的文章
[Zhang, Feifang]的文章
百度学术
百度学术中相似的文章
[Jin, Gaowa]的文章
[Xue, Xingya]的文章
[Zhang, Feifang]的文章
必应学术
必应学术中相似的文章
[Jin, Gaowa]的文章
[Xue, Xingya]的文章
[Zhang, Feifang]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。