DICP OpenIR
Micropumps actuated negative pressure injection for microchip electrophoresis
Li, Bowei1,2; Jiang, Lei1; Wang, Qi3; Oin, Jianhua1; Lin, Bingcheng1; Lin BC(林炳承)
KeywordIntegrated Micropump Microchip Electrophoresis Negative Pressure Pinched Injection
Source PublicationELECTROPHORESIS
2008-12-01
DOI10.1002/elps.200800336
Volume29Issue:24Pages:4906-4913
Indexed BySCI
SubtypeArticle
Department18
Funding Project1807
Contribution Rank1;1
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS KeywordTOTAL ANALYSIS SYSTEMS ; MICROFLUIDIC CHIP ; CAPILLARY ELECTROPHORESIS ; HYDROSTATIC-PRESSURE ; SAMPLE INJECTION ; DEVICE ; SEPARATION ; INTEGRATION ; TECHNOLOGY ; GRAVITY
AbstractA simple negative pressure pinched sample injection method was presented. This method combined diaphragm micropumps and a single voltage supply to generate controllable well-defined sample plug, and led to effective electrophoresis separation. The pinched plug was found to be favorable for obtaining representative and reproducible results that the RSD of the migration time and peak height of sodium fluorescein were 0.5 and 2.1%, respectively (n = 25). The established method had been applied in separation of amino acid samples. This method has the advantages of well-defined plug, free sample bias effect, high reproducibility and convenience of controlling the negative pressure by the integrated pumps on the microchip. In addition, the single high voltage supply and the world-to-chip interface simplified the instrumentation, which is of benefit to the minimization and automation. These advantages demonstrate the potential of this method for a wide range of applications.
Language英语
URL查看原文
WOS IDWOS:000262565700011
Citation statistics
Cited Times:11[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/101589
Collection中国科学院大连化学物理研究所
Corresponding AuthorLin BC(林炳承)
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100864, Peoples R China
3.Dalian Med Univ, Affiliated Hosp 2, Dept Resp Dis, Dalian, Peoples R China
Recommended Citation
GB/T 7714
Li, Bowei,Jiang, Lei,Wang, Qi,et al. Micropumps actuated negative pressure injection for microchip electrophoresis[J]. ELECTROPHORESIS,2008,29(24):4906-4913.
APA Li, Bowei,Jiang, Lei,Wang, Qi,Oin, Jianhua,Lin, Bingcheng,&林炳承.(2008).Micropumps actuated negative pressure injection for microchip electrophoresis.ELECTROPHORESIS,29(24),4906-4913.
MLA Li, Bowei,et al."Micropumps actuated negative pressure injection for microchip electrophoresis".ELECTROPHORESIS 29.24(2008):4906-4913.
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