中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Graphitized macroporous carbon microarray with hierarchical mesopores as host for the fabrication of electrochemical biosensor
作者: Lu, Xianbo1;  Xiao, Yi2;  Lei, Zhibin2;  Chen, Jiping1
通讯作者: 陈吉平
关键词: Biosensor ;  Graphitized ordered macroporous carbon ;  Direct electron transfer ;  Hemoglobin ;  Hydrogen peroxide
刊名: BIOSENSORS & BIOELECTRONICS
发表日期: 2009-09-15
DOI: 10.1016/j.bios.2009.06.018
卷: 25, 期:1, 页:244-247
收录类别: SCI
文章类型: Article
部门归属: 1
项目归属: 103
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biophysics ;  Biotechnology & Applied Microbiology ;  Chemistry, Analytical ;  Electrochemistry ;  Nanoscience & Nanotechnology
研究领域[WOS]: Biophysics ;  Biotechnology & Applied Microbiology ;  Chemistry ;  Electrochemistry ;  Science & Technology - Other Topics
英文摘要: A novel graphitized ordered macroporous carbon (GMC, pore size similar to 380 nm) with hierarchical mesopores (2-30 nm) and high graphitization degree was prepared by nickel-catalyzed graphitization of polystyrene arrays. The obtained GMC possessed high specific surface area, large pore volume, and good electrical conductivity, which was explored for the enzyme entrapment and biosensor fabrication by a facile method. With advantages of novel nanostructure and good electrical conductivity, direct electrochemistry of hemoglobin (a model protein) was observed on the GMC-based biocomposite with a formal potential of -0.36V (vs. Ag/AgCl) and an apparent heterogeneous electron transfer rate constant (k(s)) of 1.2 s(-1) in pH 7.0 buffer. Comparative studies revealed that GMC offered significant advantages over carbon nanotubes (CNTs) in facilitating direct electron transfer of entrapped Hb. The fabricated biosensor exhibited good sensitivity (101.6 mA cm(-2) M-1) and reproducibility, wide linear range (1-267 mu M), low detection limit (0.1 mu M), and good long-term stability for H2O2 detection. GMC proved to be a promising matrix for enzyme entrapment and biosensor fabrication, and may find wide potential applications in biomedical detection and environmental analyses. (C) 2009 Elsevier B.V. All rights reserved.
关键词[WOS]: DIRECT ELECTRON-TRANSFER ;  PEROXIDASE-ACTIVITY ;  GLUCOSE BIOSENSOR ;  CONSTRUCTION ;  FUNCTIONALIZATION ;  PROTEINS ;  SYSTEMS ;  LAYER
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000270538400040
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/101793
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Liaoning Normal Univ, Fac Chem & Chem Engn, Inst Chem Functionalized Mat, Dalian 116029, Peoples R China

Recommended Citation:
Lu, Xianbo,Xiao, Yi,Lei, Zhibin,et al. Graphitized macroporous carbon microarray with hierarchical mesopores as host for the fabrication of electrochemical biosensor[J]. BIOSENSORS & BIOELECTRONICS,2009,25(1):244-247.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Lu, Xianbo]'s Articles
 [Xiao, Yi]'s Articles
 [Lei, Zhibin]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Lu, Xianbo]‘s Articles
 [Xiao, Yi]‘s Articles
 [Lei, Zhibin]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace