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Microfluidic droplet trapping array as nanoliter reactors for gas-liquid chemical reaction
Zhang, Qingquan1,2; Zeng, Shaojiang1,2; Qin, Jianhua1; Lin, Bingcheng1; Qin JH(秦建华); Lin BC(林炳承)
关键词Droplets Gas-liquid Chemical Reaction Microfluidic Nanoliter Reactor
刊名ELECTROPHORESIS
2009-09-01
DOI10.1002/elps.200900331
30期:18页:3181-3188
收录类别SCI
文章类型Article
部门归属18
项目归属1807
产权排名1;1
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]SYSTEM ; DEVICE ; ENCAPSULATION ; SURFACTANTS ; TIME
英文摘要This article presents a simple method for trapping arrays of droplets relying on the designed microstructures of the microfluidic device, and this has been successfully used for parallel gas-liquid chemical reaction. In this approach, the trapping structure is composed of main channel, lateral channel and trapping region. Under a negative pressure, array droplets can be generated and trapped in the microstructure simultaneously, without the use of surfactant and the precise control of the flow velocity. By using a multi-layer microdevice containing the microstructures, single (pH gradient) and multiple gas-liquid reactions (metal ion-NH(3) complex reaction) can be performed in array droplets through the transmembrane diffusion of the gas. The droplets with quantitative concentration gradient can be formed by only replacing the specific membrane. The established method is simple, robust and easy to operate, demonstrating the potential of this device for droplet-based high-throughput screening.
语种英语
原文出处查看原文
WOS记录号WOS:000270446200010
引用统计
被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/102073
专题中国科学院大连化学物理研究所
通讯作者Qin JH(秦建华); Lin BC(林炳承)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Qingquan,Zeng, Shaojiang,Qin, Jianhua,et al. Microfluidic droplet trapping array as nanoliter reactors for gas-liquid chemical reaction[J]. ELECTROPHORESIS,2009,30(18):3181-3188.
APA Zhang, Qingquan,Zeng, Shaojiang,Qin, Jianhua,Lin, Bingcheng,秦建华,&林炳承.(2009).Microfluidic droplet trapping array as nanoliter reactors for gas-liquid chemical reaction.ELECTROPHORESIS,30(18),3181-3188.
MLA Zhang, Qingquan,et al."Microfluidic droplet trapping array as nanoliter reactors for gas-liquid chemical reaction".ELECTROPHORESIS 30.18(2009):3181-3188.
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