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The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics
Wu, Zeming1; Huang, Zhiqiang2; Lehmann, Rainer3; Zhao, Chunxia1; Xu, Guowang1; Xu GW(许国旺)
关键词Column Liquid Chromatography Gas Chromatography Mass Spectrometry Metabonomics Metabolomics Metabolic Profiling Analysis
刊名CHROMATOGRAPHIA
2009
DOI10.1365/s10337-009-0956-8
69页:S23-S32
收录类别SCI
文章类型Review
部门归属18
项目归属1808
产权排名1;1
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]PERFORMANCE LIQUID-CHROMATOGRAPHY ; 2-DIMENSIONAL GAS-CHROMATOGRAPHY ; HYDROPHILIC INTERACTION CHROMATOGRAPHY ; MULTIVARIATE STATISTICAL-ANALYSIS ; ZUCKER RAT URINE ; LC-MS ; CAPILLARY-ELECTROPHORESIS ; TOF-MS ; GC-MS ; ESCHERICHIA-COLI
英文摘要The widespread availability, suitability, and high sensitivity of chromatogrophy-mass spectrometry for chemical profiling analysis of multi-component biosamples are demonstrated by the comprehensive analysis of metabolites in all kind of biofluids or tissue and cell extracts. This review provides an overview of current chromatographic-mass spectrometric metabonomic methods and applications. The focus is on the description of global metabolic profiling techniques as well as on additional important aspects of metabonomics research such as sample pretreatment and information mining methods including strategies for the identification of potential biomarkers.
语种英语
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WOS记录号WOS:000266557100005
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被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/102155
专题中国科学院大连化学物理研究所
通讯作者Xu GW(许国旺)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Hunan Entry Exit Inspect Quarantine Bur Peoples R, Ctr Technol, Changsha 410004, Hunan, Peoples R China
3.Univ Tubingen Hosp, Cent Lab, Div Clin Chem & Pathobiochem, D-72076 Tubingen, Germany
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GB/T 7714
Wu, Zeming,Huang, Zhiqiang,Lehmann, Rainer,et al. The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics[J]. CHROMATOGRAPHIA,2009,69:S23-S32.
APA Wu, Zeming,Huang, Zhiqiang,Lehmann, Rainer,Zhao, Chunxia,Xu, Guowang,&许国旺.(2009).The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics.CHROMATOGRAPHIA,69,S23-S32.
MLA Wu, Zeming,et al."The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics".CHROMATOGRAPHIA 69(2009):S23-S32.
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