DICP OpenIR
The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics
Wu, Zeming1; Huang, Zhiqiang2; Lehmann, Rainer3; Zhao, Chunxia1; Xu, Guowang1; Xu GW(许国旺)
KeywordColumn Liquid Chromatography Gas Chromatography Mass Spectrometry Metabonomics Metabolomics Metabolic Profiling Analysis
Source PublicationCHROMATOGRAPHIA
2009
DOI10.1365/s10337-009-0956-8
Volume69Pages:S23-S32
Indexed BySCI
SubtypeReview
Department18
Funding Project1808
Contribution Rank1;1
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS KeywordPERFORMANCE LIQUID-CHROMATOGRAPHY ; 2-DIMENSIONAL GAS-CHROMATOGRAPHY ; HYDROPHILIC INTERACTION CHROMATOGRAPHY ; MULTIVARIATE STATISTICAL-ANALYSIS ; ZUCKER RAT URINE ; LC-MS ; CAPILLARY-ELECTROPHORESIS ; TOF-MS ; GC-MS ; ESCHERICHIA-COLI
AbstractThe widespread availability, suitability, and high sensitivity of chromatogrophy-mass spectrometry for chemical profiling analysis of multi-component biosamples are demonstrated by the comprehensive analysis of metabolites in all kind of biofluids or tissue and cell extracts. This review provides an overview of current chromatographic-mass spectrometric metabonomic methods and applications. The focus is on the description of global metabolic profiling techniques as well as on additional important aspects of metabonomics research such as sample pretreatment and information mining methods including strategies for the identification of potential biomarkers.
Language英语
URL查看原文
WOS IDWOS:000266557100005
Citation statistics
Cited Times:29[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/102155
Collection中国科学院大连化学物理研究所
Corresponding AuthorXu GW(许国旺)
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Hunan Entry Exit Inspect Quarantine Bur Peoples R, Ctr Technol, Changsha 410004, Hunan, Peoples R China
3.Univ Tubingen Hosp, Cent Lab, Div Clin Chem & Pathobiochem, D-72076 Tubingen, Germany
Recommended Citation
GB/T 7714
Wu, Zeming,Huang, Zhiqiang,Lehmann, Rainer,et al. The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics[J]. CHROMATOGRAPHIA,2009,69:S23-S32.
APA Wu, Zeming,Huang, Zhiqiang,Lehmann, Rainer,Zhao, Chunxia,Xu, Guowang,&许国旺.(2009).The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics.CHROMATOGRAPHIA,69,S23-S32.
MLA Wu, Zeming,et al."The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics".CHROMATOGRAPHIA 69(2009):S23-S32.
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