DICP OpenIR
A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon
Lu, Xianbo1; Xiao, Yi2; Lei, Zhibin2; Chen, Jiping1; Zhang, Haijun1; Ni, Yuwen1; Zhang, Qing1; Chen JP(陈吉平)
Source PublicationJOURNAL OF MATERIALS CHEMISTRY
2009
DOI10.1039/b903179k
Volume19Issue:27Pages:4707-4714
Indexed BySCI
SubtypeArticle
Department1
Funding Project103
Contribution Rank1;1
WOS HeadingsScience & Technology ; Physical Sciences ; Technology
WOS SubjectChemistry, Physical ; Materials Science, Multidisciplinary
WOS Research AreaChemistry ; Materials Science
WOS KeywordDIRECT ELECTRON-TRANSFER ; HYDROGEN-PEROXIDE BIOSENSOR ; IMMOBILIZED ENZYMES ; CATALYTIC ACTIVITY ; HEME-PROTEINS ; HEMOGLOBIN ; SILICA ; ELECTROCATALYSIS ; CONSTRUCTION ; STABILITY
AbstractThree dimensional ordered graphitized mesoporous carbon GMC-6 (pore diameter similar to 6 nm) and GMC-13 (pore diameter similar to 13 nm), prepared by a nickel-catalyzed template-assisted method, were explored systematically for the construction of enzyme-based electrochemical biosensors. Comparative studies revealed that GMC-6 offer significant advantages over GMC-13 and graphitized multiwalled carbon nanotubes (CNTs) in facilitating the direct electron transfer of entrapped hemoglobin and improving the performance of fabricated biosensors. The possible factors that affect the biosensing performance of these carbon materials were evaluated comprehensively and comparatively based on the characterization of their physical parameters. The biosensor based on GMC-6 displayed excellent analytical performance over a wide linear range along with good stability and selectivity for the detection of hydrogen peroxide. The "entrapment'' immobilization mode and "interspace confinement effect'' (by restraining the unfolding or conformational change of enzyme molecules from inactivation) provided by GMC can result in pore-size-dependent enzymatic stability and bioactivity, which might be a crucial factor for the superior biosensing performance of GMC-6 to that of CNTs and GMC-13. Graphitized ordered mesoporous carbons with good pore size matching for enzymes proved to be a promising electrochemical biosensing platform.
Language英语
URL查看原文
WOS IDWOS:000267571800007
Citation statistics
Cited Times:36[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/102471
Collection中国科学院大连化学物理研究所
Corresponding AuthorChen JP(陈吉平)
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Liaoning Normal Univ, Inst Chem Functionalized Mat, Fac Chem & Chem Engn, Dalian 116029, Peoples R China
Recommended Citation
GB/T 7714
Lu, Xianbo,Xiao, Yi,Lei, Zhibin,et al. A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon[J]. JOURNAL OF MATERIALS CHEMISTRY,2009,19(27):4707-4714.
APA Lu, Xianbo.,Xiao, Yi.,Lei, Zhibin.,Chen, Jiping.,Zhang, Haijun.,...&陈吉平.(2009).A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon.JOURNAL OF MATERIALS CHEMISTRY,19(27),4707-4714.
MLA Lu, Xianbo,et al."A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon".JOURNAL OF MATERIALS CHEMISTRY 19.27(2009):4707-4714.
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