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Synthesis and Application of Prenyl-Derived Photoaffinity Probes
Li Lingdong1,2; Tang Wei1,2; Zhao Zongbao1; Zhao ZB(赵宗保)
关键词Isoprenoid Chain Chemical Probe Photoaffinity Labeling Click Chemistry Chemical Proteomics
刊名CHINESE JOURNAL OF CHEMISTRY
2009-07-01
27期:7页:1391-1396
收录类别SCI ; IC
文章类型Article
部门归属18
项目归属1816
产权排名1;1
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]GERANYLGERANYLTRANSFERASE TYPE-I ; HISTONE DEACETYLASE COMPLEXES ; PROTEIN FARNESYLTRANSFERASE ; FARNESYL TRANSFERASE ; DIPHOSPHATE ANALOGS ; ESTERS ; PRENYLTRANSFERASES ; CYCLOADDITION ; BIOCHEMISTRY ; INHIBITORS
英文摘要Three photoaffinity probes containing isoprenoid chains and an azide group were synthesized using one-pot coupling reaction as the key step. The capability of these probes as labeling agents for isoprenoid chain-interacting proteins from Saccharomyces cerevisiae proteome was validated by photoaffinity reaction and "click" conjunction with the biotin reporter followed by streptavidin blot analysis.
语种英语
原文出处查看原文
WOS记录号WOS:000268625200031
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被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/102571
专题中国科学院大连化学物理研究所
通讯作者Zhao ZB(赵宗保)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Liaoning, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
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GB/T 7714
Li Lingdong,Tang Wei,Zhao Zongbao,et al. Synthesis and Application of Prenyl-Derived Photoaffinity Probes[J]. CHINESE JOURNAL OF CHEMISTRY,2009,27(7):1391-1396.
APA Li Lingdong,Tang Wei,Zhao Zongbao,&赵宗保.(2009).Synthesis and Application of Prenyl-Derived Photoaffinity Probes.CHINESE JOURNAL OF CHEMISTRY,27(7),1391-1396.
MLA Li Lingdong,et al."Synthesis and Application of Prenyl-Derived Photoaffinity Probes".CHINESE JOURNAL OF CHEMISTRY 27.7(2009):1391-1396.
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