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题名: ArMone: A Software Suite Specially Designed for Processing and Analysis of Phosphoproteome Data
作者: Jiang, Xinning1, 2;  Ye, Mingliang1;  Cheng, Kai1, 2;  Zou, Hanfa1
通讯作者: 邹汉法
关键词: phosphoproteome analysis ;  automatic validation ;  bioinformatics ;  software
刊名: JOURNAL OF PROTEOME RESEARCH
发表日期: 2010-05-01
DOI: 10.1021/pr9009904
卷: 9, 期:5, 页:2743-2751
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1809
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Biochemical Research Methods
研究领域[WOS]: Biochemistry & Molecular Biology
英文摘要: The development of new phosphoproteomic technologies has led to a rapid increase in the number of phosphoprotein identifications. Managing and extracting valuable information from the phosphoproteome data sets and generating output information in user-friendly formats require special data management and process platform. Even though a few proteome pipelines have been developed, they are mainly designed for processing data set of unmodified peptide/protein identifications. Because of the different characteristics of phosphorylated peptides/proteins, these pipelines are inconvenient, sometimes inappropriate, to process the phosphoproteome data sets. In this study, a software suite named ArMone was specially designed for the management and analysis of phosphoproteome data. It can readily identify phosphopeptides with high reliability and high sensitivity, and can effectively pinpoint the most probable phosphorylation site. A few well-designed postvalidation process tools are also available to extract and export valuable information. ArMone is a stand-alone application with friendly graphic user interface. It can run on different operating systems and can process data sets obtained by most of the commonly used database search engines.
关键词[WOS]: TANDEM MASS-SPECTRA ;  PHOSPHORYLATION ANALYSIS ;  PROTEIN-PHOSPHORYLATION ;  PEPTIDE IDENTIFICATION ;  SPECTROMETRY ;  PROTEOMICS ;  PHOSPHOPEPTIDES ;  CHROMATOGRAPHY ;  ENRICHMENT
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000277353200063
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/103091
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

Recommended Citation:
Jiang, Xinning,Ye, Mingliang,Cheng, Kai,et al. ArMone: A Software Suite Specially Designed for Processing and Analysis of Phosphoproteome Data[J]. JOURNAL OF PROTEOME RESEARCH,2010,9(5):2743-2751.
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