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Hydro-spinning: A novel technology for making alginate/chitosan fibrous scaffold
Wang, Jian-Zheng1,2; Huang, Xiao-Bo1,2; Xiao, Jing1,2; Yu, Wei-Ting1; Wang, Wei1; Xie, Wei-Yang1; Zhang, Ying1; Ma, Xiao-Jun1; Ma XJ(马小军)
关键词Hydro-spinning Alginate Chitosan Fiber Polyelectrolyte Complex (Pec)
刊名JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
2010-06-01
DOI10.1002/jbm.a.32590
93A期:3页:910-919
收录类别SCI
文章类型Article
部门归属18
项目归属1802
产权排名1;1
WOS标题词Science & Technology ; Technology
类目[WOS]Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]Engineering ; Materials Science
关键词[WOS]EXTENSIONAL FLOW ; SODIUM ALGINATE ; SHEAR-FLOW ; CHITOSAN ; FIBERS ; NANOFIBERS ; MORPHOLOGY ; VISCOSITY ; DYNAMICS ; OXIDE)
英文摘要Alginate/chitosan polyelectrolyte complex (PEC) hybrid fibers are promising materials for scaffold-making in tissue engineering. In this study, a new method termed "hydro-spinning" was developed to make alginate/chitosan hybrid fibers. In hydro-spinning, a chitosan solution was pumped into a flowing sodium alginate solution and sheared into streamlines. These elongated streamlines subsequently transformed into alginate/chitosan PEC ribbon-like fibers before breaking up into pieces. Average diameter and chitosan content of the fibers correlated positively with the chitosan concentration used in spinning. These hybrid fibers showed a high water-absorbability of around 50-fold to 60-fold of water to their dry weight and could retain their integrity after saturation in minimum essential medium (MEM) medium for 30 days. In vitro culture experiments demonstrated that these fibers were able to support the three-dimensional growth of MCF-7, suggesting the potential applications of these fibers in biomedical and bioengineering fields such as tissue engineering. (C) 2009 Wiley Periodicals, Inc. J Biomed Mater Res 93A: 910-919, 2010
语种英语
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WOS记录号WOS:000276916200011
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/103127
专题中国科学院大连化学物理研究所
通讯作者Ma XJ(马小军)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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Wang, Jian-Zheng,Huang, Xiao-Bo,Xiao, Jing,et al. Hydro-spinning: A novel technology for making alginate/chitosan fibrous scaffold[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,2010,93A(3):910-919.
APA Wang, Jian-Zheng.,Huang, Xiao-Bo.,Xiao, Jing.,Yu, Wei-Ting.,Wang, Wei.,...&马小军.(2010).Hydro-spinning: A novel technology for making alginate/chitosan fibrous scaffold.JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,93A(3),910-919.
MLA Wang, Jian-Zheng,et al."Hydro-spinning: A novel technology for making alginate/chitosan fibrous scaffold".JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 93A.3(2010):910-919.
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