题名: Size-selective proteolysis on mesoporous silica-based trypsin nanoreactor for low-MW proteome analysis
作者: Min, Qianhao 1, 2 ; Wu, Ren'an 2 ; Zhao, Liang 2 ; Qin, Hongqiang 2 ; Ye, Mingliang 2 ; Zhu, Jun-Jie 1 ; Zou, Hanfa 2
通讯作者: 邹汉法
; Jun-Jie Zhu
刊名: CHEMICAL COMMUNICATIONS
发表日期: 2010
DOI: 10.1039/c0cc00619j
卷: 46, 期: 33, 页: 6144-6146 收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1809
产权排名: 1;1
WOS标题词: Science & Technology
; Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: In this study, the concept of size-selective proteolysis was first described by using the mesoporous silica-based trypsin nanoreactor. For analysis of a complex protein sample, low-MW proteins were preferentially digested for identification while high-MW proteins were excluded from digestion.
关键词[WOS]: MOLECULAR-WEIGHT
; HUMAN PLASMA
; EFFICIENT PROTEOLYSIS
; ENRICHMENT
; PARTICLES
; PROTEINS
; COPOLYMER
; PEPTIDES
; TRIBLOCK
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000280868200037
Citation statistics:
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/103187
Appears in Collections: 中国科学院大连化学物理研究所_期刊论文
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作者单位: 1.Nanjing Univ, Sch Chem & Chem Engn, Key Lab Analyt Chem Life Sci, Nanjing 210093, Peoples R China 2.Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
Recommended Citation:
Min, Qianhao,Wu, Ren'an,Zhao, Liang,et al. Size-selective proteolysis on mesoporous silica-based trypsin nanoreactor for low-MW proteome analysis[J]. CHEMICAL COMMUNICATIONS,2010,46(33):6144-6146.