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Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS
Wang, Ao-Xue1; Ge, Guang-Bo2; Qi, Xiao-Yi1; Hu, Ying2; Liang, Si-Cheng2; Yang, Ling2; Tu, Cai-Xia1; Tu CX
关键词Uflc-dad-esi-ms Fuling Decoction Genipingentiobioside Geniposide Paeoniflorin Liquiritin
刊名FITOTERAPIA
2010-09-01
DOI10.1016/j.fitote.2010.03.016
81期:6页:662-667
收录类别SCI
文章类型Article
部门归属18
项目归属1806
产权排名2;2
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]GARDENIA-JASMINOIDES ; ANGELICA-SINENSIS ; MASS-SPECTROMETRY ; PORIA-COCOS ; PAEONIFLORIN ; QUALITY ; POLYSACCHARIDES ; CHROMATOGRAPHY ; FINGERPRINTS ; DERIVATIVES
英文摘要The traditional Chinese medicine formula Fuling Decoction (FD) has been clinically used for eczema treatment, but the unclear chemical distribution and the lack of quality control have strongly restricted its application. In this study, an analytical method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for rapid profiling of the chemical constitutes from FD. Fourteen constitutes were identified by UFLC-ESI-MS, while four major components including genipingentiobioside, geniposide, paeoniflorin and liquiritin were quantified simultaneously by UFLC-DAD. The UFLC-based method was fully validated and can be applied to screening and determination of principal components in commercially FD prescriptions. (C) 2010 Elsevier B.V. All rights reserved.
语种英语
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WOS记录号WOS:000281073800042
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/103387
专题中国科学院大连化学物理研究所
通讯作者Tu CX
作者单位1.Dalian Med Univ, Affiliated Hosp 2, Dalian, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Peoples R China
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Wang, Ao-Xue,Ge, Guang-Bo,Qi, Xiao-Yi,et al. Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS[J]. FITOTERAPIA,2010,81(6):662-667.
APA Wang, Ao-Xue.,Ge, Guang-Bo.,Qi, Xiao-Yi.,Hu, Ying.,Liang, Si-Cheng.,...&Tu CX.(2010).Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS.FITOTERAPIA,81(6),662-667.
MLA Wang, Ao-Xue,et al."Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS".FITOTERAPIA 81.6(2010):662-667.
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