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题名: Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS
作者: Wang, Ao-Xue1;  Ge, Guang-Bo2;  Qi, Xiao-Yi1;  Hu, Ying2;  Liang, Si-Cheng2;  Yang, Ling2;  Tu, Cai-Xia1
通讯作者: Tu CX
关键词: UFLC-DAD-ESI-MS ;  Fuling Decoction ;  Genipingentiobioside ;  Geniposide ;  Paeoniflorin ;  Liquiritin
刊名: FITOTERAPIA
发表日期: 2010-09-01
DOI: 10.1016/j.fitote.2010.03.016
卷: 81, 期:6, 页:662-667
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1806
产权排名: 2;2
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Chemistry, Medicinal ;  Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
英文摘要: The traditional Chinese medicine formula Fuling Decoction (FD) has been clinically used for eczema treatment, but the unclear chemical distribution and the lack of quality control have strongly restricted its application. In this study, an analytical method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for rapid profiling of the chemical constitutes from FD. Fourteen constitutes were identified by UFLC-ESI-MS, while four major components including genipingentiobioside, geniposide, paeoniflorin and liquiritin were quantified simultaneously by UFLC-DAD. The UFLC-based method was fully validated and can be applied to screening and determination of principal components in commercially FD prescriptions. (C) 2010 Elsevier B.V. All rights reserved.
关键词[WOS]: GARDENIA-JASMINOIDES ;  ANGELICA-SINENSIS ;  MASS-SPECTROMETRY ;  PORIA-COCOS ;  PAEONIFLORIN ;  QUALITY ;  POLYSACCHARIDES ;  CHROMATOGRAPHY ;  FINGERPRINTS ;  DERIVATIVES
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000281073800042
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/103387
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Dalian Med Univ, Affiliated Hosp 2, Dalian, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Peoples R China

Recommended Citation:
Wang, Ao-Xue,Ge, Guang-Bo,Qi, Xiao-Yi,et al. Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS[J]. FITOTERAPIA,2010,81(6):662-667.
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