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Self-assembly of mesoporous silicas hollow microspheres via food grade emulsifiers for delivery systems
Kapoor, Mahendra P.1; Vinu, Ajayan2; Fujii, Wataru1; Kimura, Tatsuo3; Yang, Qihua4; Kasama, Yuuki1; Yanagi, Masaaki1; Juneja, Lekh R.1; Mahendra P. Kapoor
关键词Self-assembly Hollow Microspheres Emulsifiers Food Grade Delivery Systems
刊名MICROPOROUS AND MESOPOROUS MATERIALS
2010-03-01
DOI10.1016/j.micromeso.2009.08.019
128期:1-3页:187-193
收录类别SCI
文章类型Article
部门归属5
项目归属506
产权排名4;5
WOS标题词Science & Technology ; Physical Sciences ; Technology
类目[WOS]Chemistry, Applied ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
研究领域[WOS]Chemistry ; Science & Technology - Other Topics ; Materials Science
关键词[WOS]DRUG-DELIVERY ; RELEASE ; SPHERES ; NANOPARTICLES ; PARTICLES ; MOLECULES ; MECHANISM ; CARRIERS
英文摘要Randomly ordered mesoporous silicas hollow microspheres of 20-50 mu m in diameter with distinguished characteristic of interconnected porosity (7-14 nm) of their thin outer walls are developed. Food grade emulsifier polyglycerol esters of fatty acids (PGEFA) are used as a soft-template and n-decane as a swelling agent, which was necessary for the formation of silica doped micelles to improve the mesoporous channel orientation without leading the phase transition. The interconnected pore channels that extend from the outside of the microspheres shell to its inside are used to fill the mesoporous silicas microspheres for enhanced encapsulation of VB(3) precursor and cumulative in vitro release of vitamin B(3) with considerable rate pharmacokinetics using simple pH trigger mechanism for the delivery systems. (C) 2009 Elsevier Inc. All rights reserved.
语种英语
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WOS记录号WOS:000273105800025
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被引频次:32[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/103477
专题中国科学院大连化学物理研究所
通讯作者Mahendra P. Kapoor
作者单位1.Taiyo Kagaku Co Ltd, Res & Dev, Yokaichi, Mie 5100844, Japan
2.Natl Inst Mat Sci, World Premier Int Res Ctr Mat Nanoarchitecton MAN, Tsukuba, Ibaraki 3050044, Japan
3.Natl Inst Adv Ind Sci & Technol, Adv Mfg Res Inst, Moriyama Ku, Nagoya, Aichi 4638560, Japan
4.Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China
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Kapoor, Mahendra P.,Vinu, Ajayan,Fujii, Wataru,et al. Self-assembly of mesoporous silicas hollow microspheres via food grade emulsifiers for delivery systems[J]. MICROPOROUS AND MESOPOROUS MATERIALS,2010,128(1-3):187-193.
APA Kapoor, Mahendra P..,Vinu, Ajayan.,Fujii, Wataru.,Kimura, Tatsuo.,Yang, Qihua.,...&Mahendra P. Kapoor.(2010).Self-assembly of mesoporous silicas hollow microspheres via food grade emulsifiers for delivery systems.MICROPOROUS AND MESOPOROUS MATERIALS,128(1-3),187-193.
MLA Kapoor, Mahendra P.,et al."Self-assembly of mesoporous silicas hollow microspheres via food grade emulsifiers for delivery systems".MICROPOROUS AND MESOPOROUS MATERIALS 128.1-3(2010):187-193.
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