DICP OpenIR
学科主题物理化学
Haloperoxidase from five marine sponges (demospongia) collected from China Sea
Zhang JY(张锦友); Cao XP(曹旭鹏); Zhang W(张卫); Yu XJ(虞星炬)
会议名称13th International Biotechnology Symposium and Exhibition
会议日期2008-10-12
2008-10-12
会议地点中国
页码S316/2
部门归属十八室
主办者中国科学院,中国工程院,中国教育部,中国科技部,中国国家发改委
英文摘要Thousands of organohalogen compounds have been found in marine and terrestrial organisms (Gribble, 1999). Many of these halogenated natural products have biological activities, such as antibacterial, antifungal, antiviral, and anti-inflammatory activities (Butler and Carter-Franklin, 2004). These enzymes were divided into three groups: haloperoxidases, perhydrolases, and FADH2-dependent halogenases (van Pée and Zehner, 2003). Marine sponges as the rich resource of marine natural product, including many halogenated metabolites (Nickel et al., 2001), however, are rarely reported for their halogenase activities. This study aimed to investigate the haloperoxidase activities from fivemarine sponges of Craniella australiensis, Reniochalina sp., Axinella sp., Hymeniacidon perlevis and one unidentified sponge collected from China Seas, in order to understand the distribution, role and origin of the sponge-derived halogenases. Axinella sp. and Reniochalina sp. showed bromoperoxidase activity of 9.5 U/g wet sponge and 10.6 U/g wet sponge, respectively. All five marine sponges showed iodoperoxidase and peroxidase activity, but did not exhibit chloroperoxidase activity. Preliminary purification and characterization of the haloperoxidase from Axinella sp. has been carried out to give the optimum pH at 6.0 and isoelectric point bellow physiological pH. The haloperoxidase from Axinella sp. was unstable.
语种中文
WOS记录号WOS:000208979401232
引用统计
文献类型会议论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/113096
专题中国科学院大连化学物理研究所
通讯作者Zhang W(张卫)
推荐引用方式
GB/T 7714
Zhang JY,Cao XP,Zhang W,et al. Haloperoxidase from five marine sponges (demospongia) collected from China Sea[C],2008:S316/2.
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