DICP OpenIR
学科主题物理化学
One-step process for preparation of polar/non-polar copolymerized stationary phases by using surface horizontal polymerization
Guo ZM(郭志谋); Liang T(梁图); Cai XM(蔡晓明); Ceng J(曾静); Wang CR(王超然); Liang XM(梁鑫淼)
会议名称24th International Symposium on Microscale Bioseparations
会议日期2009-10-18
2009-10-18
会议地点中国
其他题名基于表面水平聚合的极性/非极性共聚固定相制备
页码272/1
部门归属十八室
主办者中国科学院大连化物所
英文摘要Reversed-phase liquid chromatography (RPLC) is the most popular chromatographic mode for the separation of a wide variety of compounds. The traditional alkyl stationary phases for RPLC primarily complement hydrophobic interaction, while the polar interactions are limited. Polar RPLC stationary phases are developed to enhance the polar interactions in the RP separation of polar compounds. So far, there are two main approaches, e.g. polar embeded and polar endcapped, for the introduction of polar groups in RPLC stationary phases. 1 Herein, a new approach with one-step process for preparation of polar stationary phases for RPLC was proposed. In this approach, the mixture of polar silane (e. g. 3-chloridepropyltrichlorosilane) and non-polar silane (e. g. n-octadecyltrichlosilane) are copolymerized on the silica surface to afford the “polar/non-polar copolymerized stationary phase” (Figure 1) by using horizontal polymerization silanization method, which was introduced by Wirth and coworkers. 2 This new approach is facile and flexible. The types and ratios of the polar and non-polar silanes can be used for preparation of well designed stationary phases. The polar/non-polar copolymerized stationary phases demonstrated good separation efficiency and selectivity in the separation of test standards, tryptic digests of bovine serum albumin and several kinds of Traditional Chinese Medicines (TCMs).
语种中文
文献类型会议论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/113892
专题中国科学院大连化学物理研究所
通讯作者Liang XM(梁鑫淼)
推荐引用方式
GB/T 7714
Guo ZM,Liang T,Cai XM,et al. One-step process for preparation of polar/non-polar copolymerized stationary phases by using surface horizontal polymerization[C],2009:272/1.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[郭志谋]的文章
[梁图]的文章
[蔡晓明]的文章
百度学术
百度学术中相似的文章
[郭志谋]的文章
[梁图]的文章
[蔡晓明]的文章
必应学术
必应学术中相似的文章
[郭志谋]的文章
[梁图]的文章
[蔡晓明]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。