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学科主题物理化学
Effect of Surface Morphology on Protein Adsorption onto Alginate-Chitosan-Alginate(ACA) Microcapsules
Xie HG(谢红国); Zheng JN(郑佳妮); Li XX(李晓霞); Xie WY(谢威扬); Wang F(王锋); Ma XJ(马小军)
会议名称The Second International Symposium on Surface and Interface of Biomaterials
会议日期2010-1-4
2010-01-04
会议地点中国
其他题名表面粗糙度对蛋白在ACA微胶囊表面吸附的影响
页码168/1
部门归属十八室
主办者香港大学
英文摘要Alginate-chitosan-alginate (ACA) microcapsule has been widely studied as a device for the immuno-isolation and transplantation of living cells. However, long-term survival of the microencapsulated cell grafts and thus their potential clinical applications have been hampered by the pericapsular fibrotic overgrowth induced by adsorbed protein. Protein adsorption is a rather complex process and has been suggested to be influenced by several factors such as surface wettability, charge and morphology of materials. The effect of chemical compositions of biomaterial surface has already been studied experimentally and theoretically [1]. However, the effect of random surface roughness on protein adsorption is still not understood well.
语种中文
文献类型会议论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/114012
专题中国科学院大连化学物理研究所
通讯作者Ma XJ(马小军)
推荐引用方式
GB/T 7714
Xie HG,Zheng JN,Li XX,et al. Effect of Surface Morphology on Protein Adsorption onto Alginate-Chitosan-Alginate(ACA) Microcapsules[C],2010:168/1.
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