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学科主题: 物理化学
题名: Basic properties of alginate/chitosan microcapsule surfaces and their interaction with proteins
作者: Xie HG(谢红国) ;  Yu WT(于伟婷) ;  Liu XD(刘袖洞) ;  Xie WY(谢威扬) ;  Lv GJ(吕国军) ;  Wang F(王峰) ;  Ma XJ(马小军)
会议名称: Symposium on Innovative Polymers for Controlled Delivery
会议日期: 2010-9-14
出版日期: 2010-09-14
会议地点: 中国
通讯作者: 马小军
ISSN: 978-7-81137-581-7
部门归属: 十八室
主办者: 苏州大学
摘要: Surface properties such as morphology, composition, wettability and charge of alginate/chitosan (ACA) microcapsules were analyzed. The effects of surface properties on fibrinogen adsorption onto ACA microcapsules and on its in vivo biocompatibility were then evaluated. The results showed that the increase in both surface roughness and zeta potential resulted in an increase in the amount and conformational change of fibrinogen adsorbed. Microcapsules with rougher surface and higher zeta potential implanted into the peritoneal cavities of mice elicited a more severe foreign body response.
语种: 中文
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内容类型: 会议论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/114476
Appears in Collections:中国科学院大连化学物理研究所_会议论文

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Recommended Citation:
Xie HG,Yu WT,Liu XD,et al. Basic properties of alginate/chitosan microcapsule surfaces and their interaction with proteins[C]. 见:Symposium on Innovative Polymers for Controlled Delivery. 中国. 2010-9-14.
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