Subject Area物理化学
Basic properties of alginate/chitosan microcapsule surfaces and their interaction with proteins
Xie HG(谢红国); Yu WT(于伟婷); Liu XD(刘袖洞); Xie WY(谢威扬); Lv GJ(吕国军); Wang F(王峰); Ma XJ(马小军)
Conference NameSymposium on Innovative Polymers for Controlled Delivery
Conference Date2010-9-14
Conference Place中国
Funding Organization苏州大学
AbstractSurface properties such as morphology, composition, wettability and charge of alginate/chitosan (ACA) microcapsules were analyzed. The effects of surface properties on fibrinogen adsorption onto ACA microcapsules and on its in vivo biocompatibility were then evaluated. The results showed that the increase in both surface roughness and zeta potential resulted in an increase in the amount and conformational change of fibrinogen adsorbed. Microcapsules with rougher surface and higher zeta potential implanted into the peritoneal cavities of mice elicited a more severe foreign body response.
WOS IDWOS:000299125600167
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Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type会议论文
Corresponding AuthorMa XJ(马小军)
Recommended Citation
GB/T 7714
Xie HG,Yu WT,Liu XD,et al. Basic properties of alginate/chitosan microcapsule surfaces and their interaction with proteins[C],2010:555/2.
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