DICP OpenIR
Subject Area物理化学
Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei
Xu, Xiao-Hui1,2; Zhang, Wei1,3,4; Cao, Xu-Peng1; Xue, Song1; Zhang W(张卫)
KeywordAbietane Diterpenoids Elicitation In Situ Product Removal Cephalotaxus Fortunei Cell Suspension Culture
Source PublicationPHYTOCHEMISTRY LETTERS
2011-03-15
ISSN待补充
DOI10.1016/j.phytol.2010.12.003
Volume4Issue:1Pages:52-55
Indexed BySCI
SubtypeArticle
Department18
Funding Project1812
Contribution Rank1,1
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS SubjectBiochemistry & Molecular Biology ; Plant Sciences
WOS Research AreaBiochemistry & Molecular Biology ; Plant Sciences
WOS KeywordSECONDARY METABOLITES ; CALLUS ; HOMOHARRINGTONINE ; HARRINGTONINE ; YUNNANENSIS
AbstractAbietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei; Cell suspension cultures of Cephalotaxus fortunei were manipulated to produce secondary metabolites of pharmaceutical interest. Seven abietane diterpenoids (six known and one new) were produced by the suspension-cultured C. fortunei cells by complementing an elicitation strategy with an in situ product removal strategy. Based on the results of spectrometric analysis, the structure of the new compound was determined to be 20(10 -> 5)-abeo-4,5-seco-5(10), 6,8,11,13-abietapentaene-3-one (1). The six known compounds were identified as 12-hydroxyabieta-6,8,11,13-tetraene-3-one (2), abieta-8,11,13-triene-3 beta, 12-diol (hinokiol) (3), abietatriene-3 beta-ol (4), 11,12-dihydroxy-8,11,13-abietatriene-3,7-dione (5), 11-hydroxy-12-methoxyabieta-8,11,13-triene-3,7-dione (6), and 3 beta, 11-dihydroxy-12-methoxyabieta-8,11,13- triene-7-one (7). This is the first time that diterpenoids have been isolated and identified from this pharmaceutically important plant. These results suggest that the strategies we applied were effective methods for synthesizing abietane diterpenoids via a suspension culture of C. fortunei cells. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
Language英语
WOS IDWOS:000287850100010
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/115192
Collection中国科学院大连化学物理研究所
Corresponding AuthorZhang W(张卫)
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Marine Bioprod Engn Grp, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Flinders Univ S Australia, Flinders Ctr Marine Bioproc & Bioprod, Adelaide, SA 5042, Australia
4.Flinders Univ S Australia, Dept Med Biotechnol, Sch Med, Adelaide, SA 5042, Australia
Recommended Citation
GB/T 7714
Xu, Xiao-Hui,Zhang, Wei,Cao, Xu-Peng,et al. Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei[J]. PHYTOCHEMISTRY LETTERS,2011,4(1):52-55.
APA Xu, Xiao-Hui,Zhang, Wei,Cao, Xu-Peng,Xue, Song,&张卫.(2011).Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei.PHYTOCHEMISTRY LETTERS,4(1),52-55.
MLA Xu, Xiao-Hui,et al."Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei".PHYTOCHEMISTRY LETTERS 4.1(2011):52-55.
Files in This Item:
File Name/Size DocType Version Access License
2011PmZKyQAqK0.pdf(374KB) 开放获取--Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Xu, Xiao-Hui]'s Articles
[Zhang, Wei]'s Articles
[Cao, Xu-Peng]'s Articles
Baidu academic
Similar articles in Baidu academic
[Xu, Xiao-Hui]'s Articles
[Zhang, Wei]'s Articles
[Cao, Xu-Peng]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Xu, Xiao-Hui]'s Articles
[Zhang, Wei]'s Articles
[Cao, Xu-Peng]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.