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学科主题: 物理化学
题名: A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living Cells
作者: Yu, Fabiao1;  Li, Peng1;  Li, Guangyue1;  Zhao, Guangjiu1;  Chu, Tianshu1;  Han, Keli1
通讯作者: 韩克利
刊名: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
发表日期: 2011-07-27
DOI: 10.1021/ja202582x
卷: 133, 期:29, 页:11030-11033
收录类别: SCI
文章类型: Article
部门归属: 11
项目归属: 1101
产权排名: 1,1
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
摘要: A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living Cells
研究领域[WOS]: Chemistry
英文摘要: We have developed a near-IR reversible fluorescent probe containing an organoselenium functional group that can be used for the highly sensitive and selective monitoring of peroxynitrite oxidation and reduction events under physiological conditions. The probe effectively avoids the influence of autofluorescence in biological systems and gave positive results when tested in both aqueous solution and living cells. Real-time images of cellular peroxynitrite were successfully acquired.
关键词[WOS]: NITRIC-OXIDE ;  REACTIVE OXYGEN ;  GLUTATHIONE PEROXIDASE ;  ORGANOSELENIUM ;  MACROPHAGES ;  ACTIVATION ;  CHEMISTRY ;  MECHANISM ;  NEURONS ;  DISEASE
语种: 英语
WOS记录号: WOS:000293367300007
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/115371
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China

Recommended Citation:
Yu, Fabiao,Li, Peng,Li, Guangyue,et al. A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living Cells[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2011,133(29):11030-11033.
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