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学科主题: 物理化学
题名: Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases
作者: Liu, Hong-tao2;  Huang, Pei1;  Ma, Pan2;  Liu, Qi-shun1;  Yu, Chao1;  Du, Yu-guang2
通讯作者: YuC ;  杜昱光
关键词: anti-inflammatory agents ;  arteriosclerosis ;  lipopolysaccharides ;  endothelial cells ;  chemokine ;  MAPK ;  phosphatidylinositol 3-kinase ;  interleukin-8 ;  NF-kappa B ;  chitosan oligosaccharides
刊名: ACTA PHARMACOLOGICA SINICA
发表日期: 2011-04-01
DOI: 10.1038/aps.2011.10
卷: 32, 期:4, 页:478-486
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1805
产权排名: 1,1
WOS标题词: Science & Technology ;  Physical Sciences ;  Life Sciences & Biomedicine
类目[WOS]: Chemistry, Multidisciplinary ;  Pharmacology & Pharmacy
摘要: Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases
研究领域[WOS]: Chemistry ;  Pharmacology & Pharmacy
英文摘要: Aim: To investigate whether and how COS inhibited IL-8 production in LPS-induced human umbilical vein endothelial cells (HUVECs).
关键词[WOS]: FACTOR-KAPPA-B ;  INHIBITS PROINFLAMMATORY RESPONSES ;  TRANSCRIPTION FACTORS ;  INTESTINAL-CELLS ;  GROWTH-FACTOR ;  CANCER CELLS ;  U937 CELLS ;  IN-VITRO ;  ACTIVATION ;  INTERLEUKIN-8
语种: 英语
WOS记录号: WOS:000289194200009
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/115524
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chongqing Med Univ, Inst Life Sci, Chongqing 400016, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

Recommended Citation:
Liu, Hong-tao,Huang, Pei,Ma, Pan,et al. Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases[J]. ACTA PHARMACOLOGICA SINICA,2011,32(4):478-486.
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