DICP OpenIR
Subject Area物理化学
Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors
Hou, Shuhua1,2; Liu, Wujun1; Ji, Debin1,2; Wang, Qian1; Zhao, Zongbao Kent1,3; Zhao ZB(赵宗保)
KeywordNad Analogs Malic Enzyme Alcohol Dehydrogenase Promiscuity
Source PublicationTETRAHEDRON LETTERS
2011-11-02
ISSN待补充
DOI10.1016/j.tetlet.2011.08.152
Volume52Issue:44Pages:5855-5857
Indexed BySCI ; IC
SubtypeArticle
Department18
Funding Project1816
Contribution Rank1,1
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Organic
WOS Research AreaChemistry
WOS KeywordCHEMICAL-SYNTHESIS ; DEHYDROGENASE ; COENZYMES ; EVOLUTION ; RIBOSE
AbstractSynthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors; Thirteen 1,2,3-triazole moiety-containing NAD analogs were synthesized and evaluated as redox cofactors. Noticeable enzymatic activities were observed when these analogs were employed as cofactors for malic enzyme or alcohol dehydrogenase. Our results indicated that the natural NAD-dependent oxidoreductases possessed flexible NAD binding pockets. (C) 2011 Elsevier Ltd. All rights reserved.
Language英语
WOS IDWOS:000296168300033
Citation statistics
Cited Times:9[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/115573
Collection中国科学院大连化学物理研究所
Corresponding AuthorZhao ZB(赵宗保)
Affiliation1.CAS, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
3.Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Hou, Shuhua,Liu, Wujun,Ji, Debin,et al. Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors[J]. TETRAHEDRON LETTERS,2011,52(44):5855-5857.
APA Hou, Shuhua,Liu, Wujun,Ji, Debin,Wang, Qian,Zhao, Zongbao Kent,&赵宗保.(2011).Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors.TETRAHEDRON LETTERS,52(44),5855-5857.
MLA Hou, Shuhua,et al."Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors".TETRAHEDRON LETTERS 52.44(2011):5855-5857.
Files in This Item:
File Name/Size DocType Version Access License
2011TLh7gh95Le.pdf(274KB) 开放获取--Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Hou, Shuhua]'s Articles
[Liu, Wujun]'s Articles
[Ji, Debin]'s Articles
Baidu academic
Similar articles in Baidu academic
[Hou, Shuhua]'s Articles
[Liu, Wujun]'s Articles
[Ji, Debin]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Hou, Shuhua]'s Articles
[Liu, Wujun]'s Articles
[Ji, Debin]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.