DICP OpenIR
学科主题物理化学
A fully automated system with on-line micro solid-phase extraction combined with capillary liquid chromatography-tandem mass spectrometry for high throughput analysis of microcystins and nodularin-R in tap water and lake water
Shan, Yuanhong; Shi, Xianzhe; Dou, Abo; Zou, Cunjie; He, Hongbing; Yang, Qin; Zhao, Sumin; Lu, Xin; Xu, Guowang; Xu GW(许国旺)
关键词Microcystins Nodularin-r On-line Micro Solid-phase Extraction Capillary Liquid Chromatography-mass Spectrometry
刊名JOURNAL OF CHROMATOGRAPHY A
2011-04-01
ISSN待补充
DOI10.1016/j.chroma.2011.01.069
1218期:13页:1743-1748
收录类别SCI
文章类型Article
部门归属18
项目归属1808
产权排名1,1
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]CYANOBACTERIAL TOXINS ; SUPPLEMENT PRODUCTS ; SAMPLES ; MICROEXTRACTION ; BLOOMS ; LR
英文摘要A fully automated system with on-line micro solid-phase extraction combined with capillary liquid chromatography-tandem mass spectrometry for high throughput analysis of microcystins and nodularin-R in tap water and lake water; Microcystins and nodularins are cyclic peptide hepatotoxins and tumour promoters from cyanobacteria. The present study describes the development, validation and practical application of a fully automated analytical method based on on-line micro solid-phase extraction-capillary liquid chromatography-tandem mass spectrometry for the simultaneous determination of seven microcystins and nodularin-R in tap water and lake water. Aliquots of just 100 mu L of water samples are sufficient for the detection and quantification of all eight toxins. Selected reaction monitoring was used to obtain the highest sensitivity. Good linear calibrations were obtained for microcystins (50-2000 ng/L) and nodularin-R (25-1000 ng/L) in spiked tap water and lake water samples. Excellent interday and intraday repeatability were achieved for eight toxins with relative standard deviation less than 15.7% in three different concentrations. Acceptable recoveries were achieved in the three concentrations with both tap water matrix and lake water matrix and no significant matrix effect was found in tap water and lake water except for microcystin-RR. The limits of detection (signal to noise ratio = 3) of toxins were lower than 56.6 ng/L which is far below the 1 mu g/L defined by the World Health Organization provisional guideline for microcystin-LR. Finally, this method was successfully applied to lake water samples from Tai lake and proved to be useful for water quality monitoring. (C) 2011 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000288837400007
引用统计
被引频次:21[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/115665
专题中国科学院大连化学物理研究所
通讯作者Xu GW(许国旺)
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Shan, Yuanhong,Shi, Xianzhe,Dou, Abo,et al. A fully automated system with on-line micro solid-phase extraction combined with capillary liquid chromatography-tandem mass spectrometry for high throughput analysis of microcystins and nodularin-R in tap water and lake water[J]. JOURNAL OF CHROMATOGRAPHY A,2011,1218(13):1743-1748.
APA Shan, Yuanhong.,Shi, Xianzhe.,Dou, Abo.,Zou, Cunjie.,He, Hongbing.,...&许国旺.(2011).A fully automated system with on-line micro solid-phase extraction combined with capillary liquid chromatography-tandem mass spectrometry for high throughput analysis of microcystins and nodularin-R in tap water and lake water.JOURNAL OF CHROMATOGRAPHY A,1218(13),1743-1748.
MLA Shan, Yuanhong,et al."A fully automated system with on-line micro solid-phase extraction combined with capillary liquid chromatography-tandem mass spectrometry for high throughput analysis of microcystins and nodularin-R in tap water and lake water".JOURNAL OF CHROMATOGRAPHY A 1218.13(2011):1743-1748.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2011EhShCXqS7W.pdf(558KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Shan, Yuanhong]的文章
[Shi, Xianzhe]的文章
[Dou, Abo]的文章
百度学术
百度学术中相似的文章
[Shan, Yuanhong]的文章
[Shi, Xianzhe]的文章
[Dou, Abo]的文章
必应学术
必应学术中相似的文章
[Shan, Yuanhong]的文章
[Shi, Xianzhe]的文章
[Dou, Abo]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。