DICP OpenIR
学科主题物理化学
Metabolomics study of diabetic retinopathy using gas chromatography-mass spectrometry: a comparison of stages and subtypes diagnosed by Western and Chinese medicine
Li, Xiang2; Luo, Xiangxia3; Lu, Xin2; Duan, Junguo1; Xu, Guowang2; DuanJunguo; Xu GW(许国旺)
刊名MOLECULAR BIOSYSTEMS
2011
ISSN待补充
DOI10.1039/c0mb00341g
7期:7页:2228-2237
收录类别SCI
文章类型Article
部门归属18
项目归属1808
产权排名1,1
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biochemistry & Molecular Biology
研究领域[WOS]Biochemistry & Molecular Biology
关键词[WOS]POLYUNSATURATED FATTY-ACIDS ; SYSTEMS BIOLOGY ; GLUCOSE ; METABONOMICS ; SEVERITY ; DISEASE ; CONTEXT
英文摘要Metabolomics study of diabetic retinopathy using gas chromatography-mass spectrometry: a comparison of stages and subtypes diagnosed by Western and Chinese medicine; Diabetic retinopathy (DR) is a serious microvascular syndrome of diabetes, and is one of the most frequent causes of blindness in the world. It has three progressive stages with complex metabolic deregulations in the holistic system of Western medicine. Chinese medicine classifies DR into two different syndrome types; integrating Western and Chinese medicine to treat DR is a validated therapeutic approach in China. In this research, the systemic metabolite change of DR was investigated from the viewpoint of both Western and Chinese medicine, using metabolomics based on gas chromatography-mass spectrometry. The data revealed both perspectives can reflect the metabolic patterns, development and differentiation of DR, and the data also had good correlation and complementarity in characterizing the process of DR. Potential biomarkers of DR based on the two perspectives indicated the alterative modes of metabolites and metabolic pathways in the disease, e. g. the disturbance in fatty acids, amino acids and glucose, etc. The results showed the usefulness and validity of combining both Western and Chinese medicine to study the subtypes of DR and the mechanisms involved.
语种英语
WOS记录号WOS:000291559900015
引用统计
被引频次:21[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/115678
专题中国科学院大连化学物理研究所
通讯作者DuanJunguo; Xu GW(许国旺)
作者单位1.Chengdu Univ Tradit Chinese Med, Teaching Hosp, Chengdu 610075, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Gansu Prov Hosp, Dept Ophthalmol, Lanzhou 73005, Peoples R China
推荐引用方式
GB/T 7714
Li, Xiang,Luo, Xiangxia,Lu, Xin,et al. Metabolomics study of diabetic retinopathy using gas chromatography-mass spectrometry: a comparison of stages and subtypes diagnosed by Western and Chinese medicine[J]. MOLECULAR BIOSYSTEMS,2011,7(7):2228-2237.
APA Li, Xiang.,Luo, Xiangxia.,Lu, Xin.,Duan, Junguo.,Xu, Guowang.,...&许国旺.(2011).Metabolomics study of diabetic retinopathy using gas chromatography-mass spectrometry: a comparison of stages and subtypes diagnosed by Western and Chinese medicine.MOLECULAR BIOSYSTEMS,7(7),2228-2237.
MLA Li, Xiang,et al."Metabolomics study of diabetic retinopathy using gas chromatography-mass spectrometry: a comparison of stages and subtypes diagnosed by Western and Chinese medicine".MOLECULAR BIOSYSTEMS 7.7(2011):2228-2237.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2011HrVNTmEFvd.pdf(1754KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Li, Xiang]的文章
[Luo, Xiangxia]的文章
[Lu, Xin]的文章
百度学术
百度学术中相似的文章
[Li, Xiang]的文章
[Luo, Xiangxia]的文章
[Lu, Xin]的文章
必应学术
必应学术中相似的文章
[Li, Xiang]的文章
[Luo, Xiangxia]的文章
[Lu, Xin]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。