DICP OpenIR
Subject Area物理化学
Asymmetric catalysis in nanopore materials
Yang QH(杨启华)
Source PublicationOrganometallic Chemistry
Conference NameGordon Research Conference (GRC) on Organometallic Chemistry
Conference Date2011-7-10
2011
Conference Place阿岗
Alternative Title纳米笼中的不对称催化
Pages0-0
Publisher待补充
Publication Place待补充
Cooperation Status分会口头报告
Department506
Funding Organization美国阿岗国家实验室
AbstractHeterogeneous chiral catalysts, mostly solid catalysts possess inherent features of practical advantages for industrial processes, such as simple separation and reuse of chiral catalysts, easy purification of products, and convenient operation processes. Therefore heterogeneous asymmetric catalysis is becoming a fascinating area for both the academic research and the commercial applications. However, the activity and enantioselectivity of most chiral solids is not high which impedes the practical applications of heterogeneous asymmetric catalysis. Recently, the novel chiral porous materials, the chiral periodic mesoporous organosilicas, were synthesized by our group and these materials show application potentials in heterogeneous asymmetric catalysis [1]. Moreover, our group developed an efficient method for the preparation of nanoreactors for asymmetric catalysis by encapsulating transition metal complexes in the nanocage of mesoporous silicas [2-5]. For example, chiral [Co(Salen)] complexes have been confined in the nanocage of SBA-16 by reducing the pore entrance size through a silylation method, resulting in a solid catalyst for the hydrolytic kinetic resolution (HKR) of epoxides. It was found that the activity of the solid catalysts increased with the number of [Co(Salen)] molecules per nanocage increasing, and the solid catalyst with more than two chiral [Co(Salen)] molecules in one nanocage of SBA-16 exhibits much higher activity and enantioselectivity than the homogeneous [Co(Salen)] catalyst in the HKR of epoxides at low substrate/catalyst ratio. The significantly improved activity of the solid catalyst is due to a high local concentration of [Co(Salen)] in nanospace because of the enhanced cooperative activation effect of [Co(Salen)] molecules. This work provides a new opportunity for the design of efficient solid catalysts for the asymmetric reactions as well as many other reactions, which involve cooperative activation by separate catalytic centers or second-order kinetic dependence on the local concentration of catalysts.; Heterogeneous chiral catalysts, mostly solid catalysts possess inherent features of practical advantages for industrial processes, such as simple separation and reuse of chiral catalysts, easy purification of products, and convenient operation processes. Therefore heterogeneous asymmetric catalysis is becoming a fascinating area for both the academic research and the commercial applications. However, the activity and enantioselectivity of most chiral solids is not high which impedes the practical applications of heterogeneous asymmetric catalysis. Recently, the novel chiral porous materials, the chiral periodic mesoporous organosilicas, were synthesized by our group and these materials show application potentials in heterogeneous asymmetric catalysis [1]. Moreover, our group developed an efficient method for the preparation of nanoreactors for asymmetric catalysis by encapsulating transition metal complexes in the nanocage of mesoporous silicas [2-5]. For example, chiral [Co(Salen)] complexes have been confined in the nanocage of SBA-16 by reducing the pore entrance size through a silylation method, resulting in a solid catalyst for the hydrolytic kinetic resolution (HKR) of epoxides. It was found that the activity of the solid catalysts increased with the number of [Co(Salen)] molecules per nanocage increasing, and the solid catalyst with more than two chiral [Co(Salen)] molecules in one nanocage of SBA-16 exhibits much higher activity and enantioselectivity than the homogeneous [Co(Salen)] catalyst in the HKR of epoxides at low substrate/catalyst ratio. The significantly improved activity of the solid catalyst is due to a high local concentration of [Co(Salen)] in nanospace because of the enhanced cooperative activation effect of [Co(Salen)] molecules. This work provides a new opportunity for the design of efficient solid catalysts for the asymmetric reactions as well as many other reactions, which involve cooperative activation by separate catalytic centers or second-order kinetic dependence on the local concentration of catalysts.
Language英语
Document Type会议论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/115962
Collection中国科学院大连化学物理研究所
Corresponding AuthorYang QH(杨启华)
Recommended Citation
GB/T 7714
Yang QH. Asymmetric catalysis in nanopore materials[C]. 待补充:待补充,2011:0-0.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[杨启华]'s Articles
Baidu academic
Similar articles in Baidu academic
[杨启华]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[杨启华]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.