中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 会议论文
学科主题: 分析化学
题名: A functional metabolomics platform based on non-target and target chromatography-mass spectrometry
作者: Xu GW(许国旺) ;  Zhao XJ(赵欣捷) ;  Hu CX(胡春秀) ;  Wang XL(王晓琳) ;  Chen SL(陈世礼) ;  Li J(李佳)
会议文集: 2011 Annual meeting of KSMS & 2nd AOMSC
会议名称: The 2nd Asian and Oceanic Mass Spectrometry Conference
会议日期: 2011-8-17
出版日期: 2011
会议地点: 釜山
通讯作者: 许国旺
出版者: 待补充
出版地: 待补充
合作性质: 分会特邀报告
部门归属: 1808
主办者: Korean Society for Mass Spectrometry
摘要: Recently the detection of biomarkers by targeted and non-targeted metabolomics studies is continuously increasing with a special focus on complicated disease research especially on diagnosis and treatment of metabolic diseases. However, until now the majority of studies are descriptive, only the differences in the relative or absolute contents were reported, very few dealt with the function of differential metabolites, Most of the explanation on the function of the detected so-called biomarkers, if there was, was based on the literatures. In this lecture, we shall report a functional metabolomics platform including tissue-specific cell culture with isotope-labelled compounds, target and non-target analyses based on the var-ious chromatography - mass spectrometry methods and multi-variable analysis data analysis. The prediabete and exercise studies will be used as the examples to show the usefulness of our platform. It is expected that the functional metabolomics study will improve current knowledge on the regulation of metabolic processes in health and disease states, it is helpful to find new therapeutic targets for diseases.
英文摘要: Recently the detection of biomarkers by targeted and non-targeted metabolomics studies is continuously increasing with a special focus on complicated disease research especially on diagnosis and treatment of metabolic diseases. However, until now the majority of studies are descriptive, only the differences in the relative or absolute contents were reported, very few dealt with the function of differential metabolites, Most of the explanation on the function of the detected so-called biomarkers, if there was, was based on the literatures. In this lecture, we shall report a functional metabolomics platform including tissue-specific cell culture with isotope-labelled compounds, target and non-target analyses based on the var-ious chromatography - mass spectrometry methods and multi-variable analysis data analysis. The prediabete and exercise studies will be used as the examples to show the usefulness of our platform. It is expected that the functional metabolomics study will improve current knowledge on the regulation of metabolic processes in health and disease states, it is helpful to find new therapeutic targets for diseases.
内容类型: 会议论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/116059
Appears in Collections:中国科学院大连化学物理研究所_会议论文

Files in This Item:

There are no files associated with this item.


Recommended Citation:
Xu GW,Zhao XJ,Hu CX,et al. A functional metabolomics platform based on non-target and target chromatography-mass spectrometry[C]. 见:The 2nd Asian and Oceanic Mass Spectrometry Conference. 釜山. 2011-8-17.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [许国旺]'s Articles
 [赵欣捷]'s Articles
 [胡春秀]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [许国旺]‘s Articles
 [赵欣捷]‘s Articles
 [胡春秀]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace