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学科主题: 物理化学
题名: Development of multicolor carbon nanoparticles for cell imaging
作者: Yan, Huiping1, 2;  Tan, Mingqian2;  Zhang, Demeng2;  Cheng, Fansheng3;  Wu, Hao2;  Fan, Meikun3;  Ma, Xiaojun2;  Wang, Jihui1
通讯作者: 谭明乾
关键词: Multicolor carbon nanoparticles ;  Fluorescence ;  Cell labeling
刊名: TALANTA
发表日期: 2013-04-15
DOI: 10.1016/j.talanta.2013.02.074
卷: 108, 页:59-65
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1802
产权排名: 2,1
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: Multicolor carbon nanoparticles (CNPs) were prepared, characterized and developed as fluorescent probes for cell imaging. The fluorescent CNPs were prepared with a facile hydrothermal oxidation route by using linear polysaccharide cellulose and cyclic oligosaccharide cyclodextrin as carbon sources. The characterizations by transmission electron microscopy show that the prepared cellulose-CNPs and cyclodextrin-CNPs are spherical, well-dispersed in water with average diameters of 100 nm and 76 nm, respectively. Under the excitation of UV light, the CNPs are strongly luminescent with an excitation-dependent emission behavior and bathochromic emission properties. The fluorometric methods show that the cellulose-CNPs and cyclodextrin-CNPs are strongly fluorescent with fluorescence quantum yield of 7.47% and 4.49%, respectively. The multicolor CNPs have excellent photostability toward photobleaching. Strong near-infrared fluorescence of the carbon nanoparticles was observed with a 632.8 nm excitation wavelength laser. The oxidative metal ions like Hg(II), Cu(II) and Fe(III) show an quench effect on the fluorescence intensity of the CNPs. The multicolor CNPs were successfully used as fluorescent probes for mouse melanoma cells imaging. The results indicate that the multicolor CNPs derived from cellulose and cyclodextrin may have a great potential for the applications in bioimaging. (c) 2013 Elsevier B.V. All rights reserved.
关键词[WOS]: RESOLVED FLUOROMETRIC APPLICATION ;  QUANTUM DOTS ;  SILICA NANOPARTICLES ;  NANOTUBE ;  PHOTOLUMINESCENCE ;  NANOCRYSTALS ;  PROBES
语种: 英语
WOS记录号: WOS:000319088900009
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/117550
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Dalian Polytech Univ, Sch Food Sci & Technol, Dalian 116034, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
3.Chengdu Green Energy & Green Mfg Technol R&D Ctr, Chengdu 610207, Peoples R China

Recommended Citation:
Yan, Huiping,Tan, Mingqian,Zhang, Demeng,et al. Development of multicolor carbon nanoparticles for cell imaging[J]. TALANTA,2013,108:59-65.
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