DICP OpenIR
Subject Area物理化学
Development of multicolor carbon nanoparticles for cell imaging
Yan, Huiping1,2; Tan, Mingqian2; Zhang, Demeng2; Cheng, Fansheng3; Wu, Hao2; Fan, Meikun3; Ma, Xiaojun2; Wang, Jihui1; Tan MQ(谭明乾)
KeywordMulticolor Carbon Nanoparticles Fluorescence Cell Labeling
Source PublicationTALANTA
2013-04-15
DOI10.1016/j.talanta.2013.02.074
Volume108Pages:59-65
Indexed BySCI
SubtypeArticle
Department18
Funding Project1802
Contribution Rank2,1
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordRESOLVED FLUOROMETRIC APPLICATION ; QUANTUM DOTS ; SILICA NANOPARTICLES ; NANOTUBE ; PHOTOLUMINESCENCE ; NANOCRYSTALS ; PROBES
AbstractMulticolor carbon nanoparticles (CNPs) were prepared, characterized and developed as fluorescent probes for cell imaging. The fluorescent CNPs were prepared with a facile hydrothermal oxidation route by using linear polysaccharide cellulose and cyclic oligosaccharide cyclodextrin as carbon sources. The characterizations by transmission electron microscopy show that the prepared cellulose-CNPs and cyclodextrin-CNPs are spherical, well-dispersed in water with average diameters of 100 nm and 76 nm, respectively. Under the excitation of UV light, the CNPs are strongly luminescent with an excitation-dependent emission behavior and bathochromic emission properties. The fluorometric methods show that the cellulose-CNPs and cyclodextrin-CNPs are strongly fluorescent with fluorescence quantum yield of 7.47% and 4.49%, respectively. The multicolor CNPs have excellent photostability toward photobleaching. Strong near-infrared fluorescence of the carbon nanoparticles was observed with a 632.8 nm excitation wavelength laser. The oxidative metal ions like Hg(II), Cu(II) and Fe(III) show an quench effect on the fluorescence intensity of the CNPs. The multicolor CNPs were successfully used as fluorescent probes for mouse melanoma cells imaging. The results indicate that the multicolor CNPs derived from cellulose and cyclodextrin may have a great potential for the applications in bioimaging. (c) 2013 Elsevier B.V. All rights reserved.
Language英语
WOS IDWOS:000319088900009
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/117550
Collection中国科学院大连化学物理研究所
Corresponding AuthorTan MQ(谭明乾)
Affiliation1.Dalian Polytech Univ, Sch Food Sci & Technol, Dalian 116034, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
3.Chengdu Green Energy & Green Mfg Technol R&D Ctr, Chengdu 610207, Peoples R China
Recommended Citation
GB/T 7714
Yan, Huiping,Tan, Mingqian,Zhang, Demeng,et al. Development of multicolor carbon nanoparticles for cell imaging[J]. TALANTA,2013,108:59-65.
APA Yan, Huiping.,Tan, Mingqian.,Zhang, Demeng.,Cheng, Fansheng.,Wu, Hao.,...&谭明乾.(2013).Development of multicolor carbon nanoparticles for cell imaging.TALANTA,108,59-65.
MLA Yan, Huiping,et al."Development of multicolor carbon nanoparticles for cell imaging".TALANTA 108(2013):59-65.
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