DICP OpenIR
学科主题物理化学
A novel ionic-bonded cellulose stationary phase for saccharide separation
Sheng, Qianying1; Ke, Yanxiong1; Li, Kuiyong1; Yu, Dongping2; Liang, Xinmiao1,2; Ke YX(柯燕雄); Liang XM(梁鑫淼)
关键词Cellulose-coated Stationary Phase Ion interactIon Saccharide Separation Hydrophilic Interaction Liquid Chromatography High-performance Liquid Chromatography Maldi-qit-tof-ms
刊名JOURNAL OF CHROMATOGRAPHY A
2013-05-24
DOI10.1016/j.chroma.2013.03.045
1291页:56-63
收录类别SCI
文章类型Article
部门归属18
项目归属1803
产权排名2,4
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]HYDROPHILIC-INTERACTION CHROMATOGRAPHY ; INTERACTION LIQUID-CHROMATOGRAPHY ; ANION-EXCHANGE CHROMATOGRAPHY ; MASS-SPECTROMETRY ; POLAR COMPOUNDS ; REVERSED-PHASE ; PEPTIDES ; OLIGOSACCHARIDE ; ARRAYS
英文摘要A hydrophilic interaction liquid chromatography (HILIC) stationary phase of cellulose-coated silica was synthesized as a novel saccharide separation material. The material, prepared with a method based on ionic interaction, was demonstrated to be efficient for immobilization of saccharides on silica supports. The method is more efficient than traditional immobilized saccharide stationary phase synthesis methods. It was evolved from a method using anion exchanger microparticles agglomerated onto macroparticles of cation exchangers to produce anion exchangers. Cationic cellulose, which has a large number of hydroxyl groups, was immobilized on sulfonated silica. The cellulose-coated stationary phase we designed used strong hydrogen bonding between cellulose hydroxyl and carbohydrate compounds for HILIC retention and separation. The stationary phase was successfully used to separate the samples of polar compounds and the complex samples of oligosaccharides, and demonstrated good reproducibility and stability. The material exhibited good separation selectivity for carbohydrates and ability to enrich glycosylated peptides. The method described here is easy to achieve, environmentally safe and innovative than other methods. It also has extensive application possibilities to separate other categories polar compounds. (C) 2013 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000318745400008
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/117578
专题中国科学院大连化学物理研究所
通讯作者Ke YX(柯燕雄); Liang XM(梁鑫淼)
作者单位1.E China Univ Sci & Technol, Sch Pharm, Minist Educ, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Sheng, Qianying,Ke, Yanxiong,Li, Kuiyong,et al. A novel ionic-bonded cellulose stationary phase for saccharide separation[J]. JOURNAL OF CHROMATOGRAPHY A,2013,1291:56-63.
APA Sheng, Qianying.,Ke, Yanxiong.,Li, Kuiyong.,Yu, Dongping.,Liang, Xinmiao.,...&梁鑫淼.(2013).A novel ionic-bonded cellulose stationary phase for saccharide separation.JOURNAL OF CHROMATOGRAPHY A,1291,56-63.
MLA Sheng, Qianying,et al."A novel ionic-bonded cellulose stationary phase for saccharide separation".JOURNAL OF CHROMATOGRAPHY A 1291(2013):56-63.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2013pQJ35nfIPr.PDF(1637KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Sheng, Qianying]的文章
[Ke, Yanxiong]的文章
[Li, Kuiyong]的文章
百度学术
百度学术中相似的文章
[Sheng, Qianying]的文章
[Ke, Yanxiong]的文章
[Li, Kuiyong]的文章
必应学术
必应学术中相似的文章
[Sheng, Qianying]的文章
[Ke, Yanxiong]的文章
[Li, Kuiyong]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。