DICP OpenIR
学科主题物理化学
Recent Advancement of Chemical Derivatization and Its Applications to High Sensitive Analysis of Peptide in Mass Spectrometry
Qiao Xiao-Qiang1,2,3; Wang Rui1,2; Zhang Li-Hua3; Yang Geng-Liang1,2; Zhang Yu-Kui3; Qiao XQ(乔晓强)
关键词Chemical Derivatization High Sensitive Detection Mass Spectrometry Peptide Review
刊名CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
2012-07-01
DOI10.1016/S1872-2040(11)60560-4
40期:7页:1123-1129
收录类别SCI
文章类型Review
部门归属18
项目归属1810
产权排名2,1
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]ASSISTED-LASER-DESORPTION/IONIZATION ; MALDI-QIT-TOFMSN ; ELECTROSPRAY-IONIZATION ; STRUCTURAL DETERMINATION ; SIGNAL ENHANCEMENT ; TRYPTIC PEPTIDES ; MS/MS ANALYSIS ; AMINO-GROUPS ; MATRIX ; OLIGOSACCHARIDES
英文摘要Shotgun based strategy is a widely used method in proteome research. However, due to the high complexity and wide dynamic range, the detection sensitivity of peptides, especially for those with low abundance and low ionization efficiency, still can hardly meet the requirements. Chemical derivatization has been proved to be one of the most promising methods. Herein, the recent progress in the development of derivatization reagents targeting for the peptides as well as those with post-translational modifications, and its applications in high sensitive analysis in mass spectrometry are reviewed. Furthermore, the future research directions and the potential application in proteome research are discussed.
语种英语
WOS记录号WOS:000308253300005
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/117804
专题中国科学院大连化学物理研究所
通讯作者Qiao XQ(乔晓强)
作者单位1.Hebei Univ, Key Lab Pharmaceut Qual Control Hebei Prov, Baoding 071002, Peoples R China
2.Hebei Univ, Coll Pharmaceut Sci, Baoding 071002, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Qiao Xiao-Qiang,Wang Rui,Zhang Li-Hua,et al. Recent Advancement of Chemical Derivatization and Its Applications to High Sensitive Analysis of Peptide in Mass Spectrometry[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2012,40(7):1123-1129.
APA Qiao Xiao-Qiang,Wang Rui,Zhang Li-Hua,Yang Geng-Liang,Zhang Yu-Kui,&乔晓强.(2012).Recent Advancement of Chemical Derivatization and Its Applications to High Sensitive Analysis of Peptide in Mass Spectrometry.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,40(7),1123-1129.
MLA Qiao Xiao-Qiang,et al."Recent Advancement of Chemical Derivatization and Its Applications to High Sensitive Analysis of Peptide in Mass Spectrometry".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 40.7(2012):1123-1129.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2012VhwyI0y01z.PDF(97KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Qiao Xiao-Qiang]的文章
[Wang Rui]的文章
[Zhang Li-Hua]的文章
百度学术
百度学术中相似的文章
[Qiao Xiao-Qiang]的文章
[Wang Rui]的文章
[Zhang Li-Hua]的文章
必应学术
必应学术中相似的文章
[Qiao Xiao-Qiang]的文章
[Wang Rui]的文章
[Zhang Li-Hua]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。