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学科主题: 物理化学
题名: Analysis of Caenorhabditis elegans in microfluidic devices
作者: Wen Hui1;  Qin JianHua1
通讯作者: 秦建华
关键词: microfluidic ;  Caenorhabditis elegans ;  behavior ;  neurobiology ;  aging
刊名: SCIENCE CHINA-CHEMISTRY
发表日期: 2012-04-01
DOI: 10.1007/s11426-012-4541-x
卷: 55, 期:4, 页:484-493
收录类别: SCI
文章类型: Review
部门归属: 18
项目归属: 1807
产权排名: 1,1
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: Caenorhabditis elegans (C. elegans) is widely adopted as a model organism for a variety of biological studies including development, genetics and neurobiology. Micro-scale microfluidic technology is capable of handling single or populations of C. elegans in high throughput format and allows for the precise spatial and temporal control of their environment, which is well suited for the study of worms in different aspects. in this review, we highlight the recent advances in microfluidic technology for the analysis of worms ranging from behavioral studies to neurobiology. We believe that microfluidic device can further be applied to study the different aspects of worms, extending from fundamental investigation of behavioral dynamics to more complicated biological processes including neurochemistry and learning behaviors.
关键词[WOS]: C-ELEGANS ;  PARKINSONS-DISEASE ;  NEURONAL-ACTIVITY ;  SYSTEM ;  MODEL ;  CHIP ;  SCREENINGS ;  GENETICS ;  BEHAVIOR ;  GENOME
语种: 英语
WOS记录号: WOS:000303184300004
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/117828
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

Recommended Citation:
Wen Hui,Qin JianHua. Analysis of Caenorhabditis elegans in microfluidic devices[J]. SCIENCE CHINA-CHEMISTRY,2012,55(4):484-493.
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