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学科主题: 物理化学
题名: Synthesis of adenosine functionalized metal immobilized magnetic nanoparticles for highly selective and sensitive enrichment of phosphopeptides
作者: Zhang, Liyuan1, 2;  Zhao, Qun1, 2;  Liang, Zhen1;  Yang, Kaiguang1;  Sun, Liangliang1, 2;  Zhang, Lihua1;  Zhang, Yukui1
通讯作者: 张丽华
刊名: CHEMICAL COMMUNICATIONS
发表日期: 2012
DOI: 10.1039/c2cc31641b
卷: 48, 期:50, 页:6274-6276
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1810
产权排名: 1,1
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: A new type of IMAC material, with ATP as the chelating ligand, was synthesized and applied to capture phosphopeptides. For the first time, the approach for phosphopeptide enrichment could provide selectivity under 5000-fold dilution by nonphosphopeptides, and sensitivity of on-target enrichment at 3 amol.
关键词[WOS]: ION AFFINITY-CHROMATOGRAPHY ;  PHOSPHORYLATED PEPTIDES ;  PHOSPHOPROTEOME ANALYSIS ;  TITANIUM-DIOXIDE ;  ATP
语种: 英语
WOS记录号: WOS:000304486800021
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/117927
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

Recommended Citation:
Zhang, Liyuan,Zhao, Qun,Liang, Zhen,et al. Synthesis of adenosine functionalized metal immobilized magnetic nanoparticles for highly selective and sensitive enrichment of phosphopeptides[J]. CHEMICAL COMMUNICATIONS,2012,48(50):6274-6276.
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