DICP OpenIR
学科主题物理化学
Flexible Generation of Gradient Electrospinning Nanofibers Using a Microfluidic Assisted Approach
Zhang, Xu1,2; Gao, Xinghua1,2; Jiang, Lei1; Qin, Jianhua1; Qin JH(秦建华)
刊名LANGMUIR
2012-06-03
DOI10.1021/la300821r
28期:26页:10026-10032
收录类别SCI
文章类型Article
部门归属18
项目归属1807
产权排名1,1
WOS标题词Science & Technology ; Physical Sciences ; Technology
类目[WOS]Chemistry, Multidisciplinary ; Chemistry, Physical ; Materials Science, Multidisciplinary
研究领域[WOS]Chemistry ; Materials Science
关键词[WOS]MESENCHYMAL STEM-CELLS ; BONE DEFECTS ; SCAFFOLDS ; FIBERS ; TISSUE ; PROMOTION
英文摘要The nanofiber surface modified with physical or chemical gradients is very useful in a wide range of areas including tissue engineering, regenerative medicine, drug screening, and biomaterial chemistry. In this work, we presented a novel and straightforward microfluidic assisted approach to produce electrospinning nanofibers containing gradients in different compositions, nanoparticles and biomolecule concentrations. The series of gradient nanofibers were mainly produced by using a two inlet microfluidic device in combination with an electrospinning nozzle on a 3-D controllable platform, which exhibited different functions and properties. The controlled nanofibers with incorporated biomolecule gradient were used for guiding the spatial differentiation in mesenchymal stem cells (MSCs). This established approach is very simple, and flexible to operate, which might find enormous potential for biology and tissue engineering applications.
语种英语
WOS记录号WOS:000305869500016
引用统计
被引频次:26[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/117953
专题中国科学院大连化学物理研究所
通讯作者Qin JH(秦建华)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Xu,Gao, Xinghua,Jiang, Lei,et al. Flexible Generation of Gradient Electrospinning Nanofibers Using a Microfluidic Assisted Approach[J]. LANGMUIR,2012,28(26):10026-10032.
APA Zhang, Xu,Gao, Xinghua,Jiang, Lei,Qin, Jianhua,&秦建华.(2012).Flexible Generation of Gradient Electrospinning Nanofibers Using a Microfluidic Assisted Approach.LANGMUIR,28(26),10026-10032.
MLA Zhang, Xu,et al."Flexible Generation of Gradient Electrospinning Nanofibers Using a Microfluidic Assisted Approach".LANGMUIR 28.26(2012):10026-10032.
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