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学科主题: 物理化学
题名: Characterization of Rheumatoid Arthritis Subtypes Using Symptom Profiles, Clinical Chemistry and Metabolomics Measurements
作者: van Wietmarschen, Herman A.1, 2;  Dai, Weidong3;  van der Kooij, Anita J.4;  Reijmers, Theo H.1, 5;  Schroen, Yan2, 6;  Wang, Mei2, 7;  Xu, Zhiliang8;  Wang, Xinchang9;  Kong, Hongwei3;  Xu, Guowang3;  Hankemeier, Thomas1, 5;  Meulman, Jacqueline J.4;  van der Greef, Jan1, 2, 7, 10
通讯作者: HermanAvanWietmarschen ;  许国旺
刊名: PLOS ONE
发表日期: 2012-09-12
DOI: 10.1371/journal.pone.0044331
卷: 7, 期:9, 页:443311
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1808
产权排名: 3, 2
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
英文摘要: Objective: The aim is to characterize subgroups or phenotypes of rheumatoid arthritis (RA) patients using a systems biology approach. The discovery of subtypes of rheumatoid arthritis patients is an essential research area for the improvement of response to therapy and the development of personalized medicine strategies.
关键词[WOS]: TRADITIONAL CHINESE MEDICINE ;  PRINCIPAL-COMPONENTS-ANALYSIS ;  MASS-SPECTROMETRY ;  LIQUID-CHROMATOGRAPHY ;  DISEASE-ACTIVITY ;  ACYLCARNITINES ;  SYSTEMS ;  CLASSIFICATION ;  METABONOMICS ;  STRATEGY
语种: 英语
WOS记录号: WOS:000308738500047
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/118195
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Leiden Univ, LACDR, Div Analyt Biosci, Leiden, Netherlands
2.Sino Dutch Ctr Prevent & Personalized Med, Zeist, Netherlands
3.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China
4.Leiden Univ, Inst Math, NL-2300 RA Leiden, Netherlands
5.Leiden Univ, Netherlands Metabol Ctr, Leiden, Netherlands
6.Oxrider, Educ & Res, Nieuwegein, Netherlands
7.SU BioMed, Utrechtseweg, Zeist, Netherlands
8.Coll Life Sci Co Ltd, Hangzhou, Zhejiang, Peoples R China
9.Zhejiang Xinhua Hosp, Dept Rheumatol & Immunol, Hangzhou, Zhejiang, Peoples R China
10.TNO Pharma, TNO Netherlands Org Appl Sci Res, Zeist, Netherlands

Recommended Citation:
van Wietmarschen, Herman A.,Dai, Weidong,van der Kooij, Anita J.,et al. Characterization of Rheumatoid Arthritis Subtypes Using Symptom Profiles, Clinical Chemistry and Metabolomics Measurements[J]. PLOS ONE,2012,7(9):443311.
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