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学科主题物理化学
Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review
Wu, Qi1,2; Yuan, Huiming1; Zhang, Lihua1; Zhang, Yukui1; Zhang LH(张丽华)
关键词Multidimensional Liquid Chromatography Qualitative Analysis Quantitative Analysis Proteomics
刊名ANALYTICA CHIMICA ACTA
2012-06-20
DOI10.1016/j.aca.2012.04.010
731页:1-10
收录类别SCI
文章类型Review
部门归属18
项目归属1810
产权排名1,1
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]COMPLEX PROTEIN MIXTURES ; STRONG CATION-EXCHANGE ; CODED AFFINITY TAGS ; LABEL-FREE ; LC-MS/MS ; MEMBRANE-PROTEINS ; PEAK-CAPACITY ; SACCHAROMYCES-CEREVISIAE ; AMINO-ACIDS ; MALDI-TOF
英文摘要With the acceleration of proteome research, increasing attention has been paid to multidimensional liquid chromatography-mass spectrometry (MDLC-MS) clue to its high peak capacity and separation efficiency. Recently, many efforts have been put to improve MDLC-based strategies including "top-down" and "bottom-up" to enable highly sensitive qualitative and quantitative analysis of proteins, as well as accelerate the whole analytical procedure. Integrated platforms with combination of sample pretreatment, multidimensional separations and identification were also developed to achieve high throughput and sensitive detection of proteomes, facilitating highly accurate and reproducible quantification. This review summarized the recent advances of such techniques and their applications in qualitative and quantitative analysis of proteomes. (C) 2012 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000305380600001
引用统计
被引频次:59[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/118305
专题中国科学院大连化学物理研究所
通讯作者Zhang LH(张丽华)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
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GB/T 7714
Wu, Qi,Yuan, Huiming,Zhang, Lihua,et al. Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review[J]. ANALYTICA CHIMICA ACTA,2012,731:1-10.
APA Wu, Qi,Yuan, Huiming,Zhang, Lihua,Zhang, Yukui,&张丽华.(2012).Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review.ANALYTICA CHIMICA ACTA,731,1-10.
MLA Wu, Qi,et al."Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review".ANALYTICA CHIMICA ACTA 731(2012):1-10.
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