中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
学科主题: 物理化学
题名: Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review
作者: Wu, Qi1, 2;  Yuan, Huiming1;  Zhang, Lihua1;  Zhang, Yukui1
通讯作者: 张丽华
关键词: Multidimensional liquid chromatography ;  Qualitative analysis ;  Quantitative analysis ;  Proteomics
刊名: ANALYTICA CHIMICA ACTA
发表日期: 2012-06-20
DOI: 10.1016/j.aca.2012.04.010
卷: 731, 页:1-10
收录类别: SCI
文章类型: Review
部门归属: 18
项目归属: 1810
产权排名: 1,1
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: With the acceleration of proteome research, increasing attention has been paid to multidimensional liquid chromatography-mass spectrometry (MDLC-MS) clue to its high peak capacity and separation efficiency. Recently, many efforts have been put to improve MDLC-based strategies including "top-down" and "bottom-up" to enable highly sensitive qualitative and quantitative analysis of proteins, as well as accelerate the whole analytical procedure. Integrated platforms with combination of sample pretreatment, multidimensional separations and identification were also developed to achieve high throughput and sensitive detection of proteomes, facilitating highly accurate and reproducible quantification. This review summarized the recent advances of such techniques and their applications in qualitative and quantitative analysis of proteomes. (C) 2012 Elsevier B.V. All rights reserved.
关键词[WOS]: COMPLEX PROTEIN MIXTURES ;  STRONG CATION-EXCHANGE ;  CODED AFFINITY TAGS ;  LABEL-FREE ;  LC-MS/MS ;  MEMBRANE-PROTEINS ;  PEAK-CAPACITY ;  SACCHAROMYCES-CEREVISIAE ;  AMINO-ACIDS ;  MALDI-TOF
语种: 英语
WOS记录号: WOS:000305380600001
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/118305
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2012B2svtqDFdt.PDF(908KB)----开放获取--View Download

作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

Recommended Citation:
Wu, Qi,Yuan, Huiming,Zhang, Lihua,et al. Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review[J]. ANALYTICA CHIMICA ACTA,2012,731:1-10.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Wu, Qi]'s Articles
 [Yuan, Huiming]'s Articles
 [Zhang, Lihua]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Wu, Qi]‘s Articles
 [Yuan, Huiming]‘s Articles
 [Zhang, Lihua]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: 2012B2svtqDFdt.PDF
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace