中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
学科主题: 物理化学
题名: Retention mechanism and enrichment of glycopeptides on titanium dioxide
作者: Sheng, Qianying1;  Li, Xiuling2;  Yin, Wei3;  Yu, Long2;  Ke, Yanxiong1;  Liang, Xinmiao1, 2
通讯作者: 李秀玲 ;  梁鑫淼
刊名: ANALYTICAL METHODS
发表日期: 2013
DOI: 10.1039/c3ay41294f
卷: 5, 期:24, 页:7072-7080
收录类别: SCI
合作性质: 
文章类型: Article
部门归属: 18
项目归属: 1803
产权排名: 待补充
WOS标题词: Science & Technology ;  Physical Sciences ;  Life Sciences & Biomedicine ;  Technology
类目[WOS]: Chemistry, Analytical ;  Food Science & Technology ;  Spectroscopy
资助者: 2,2
研究领域[WOS]: Chemistry ;  Food Science & Technology ;  Spectroscopy
英文摘要: A uniform method for the facile and selective enrichment of glycopeptides with titanium dioxide (TiO2) is presented. Retention mechanisms between glycopeptides and TiO2 were explored by checking the influence of acetonitrile content, NH3 center dot H2O concentration and formic acid concentration on the retention of glycopeptides. Both hydrophilic interaction and ligand-exchange retention mechanisms between glycopeptides and TiO2 were found to be involved. Based on this, a uniform method was established for selective enrichment of glycopeptides with TiO2. The developed method exhibited high selectivity for N-linked glycopeptides with short to long peptide sequences. This efficient and uniform method will be a valuable tool for post-translational modification in proteomics.
关键词[WOS]: HYDROPHILIC INTERACTION CHROMATOGRAPHY ;  GLYCOSYLATION ;  MATRIX ;  PEPTIDES ;  HPLC
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000327506600028
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/119098
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
20132GmThBlkV5.PDF(0KB)----开放获取View 联系获取全文

作者单位: 1.E China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Sch Pharm, Shanghai 200237, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Dalian Maritime Univ, Dalian 116026, Peoples R China

Recommended Citation:
Sheng, Qianying,Li, Xiuling,Yin, Wei,et al. Retention mechanism and enrichment of glycopeptides on titanium dioxide[J]. ANALYTICAL METHODS,2013,5(24):7072-7080.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Sheng, Qianying]'s Articles
 [Li, Xiuling]'s Articles
 [Yin, Wei]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Sheng, Qianying]‘s Articles
 [Li, Xiuling]‘s Articles
 [Yin, Wei]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: 20132GmThBlkV5.PDF
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace