DICP OpenIR
Subject Area物理化学
Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles
Wang, Xiang1; Li, Shunbo2,3; Wang, Limu1; Yi, Xin1; Hui, Yu Sanna1; Qin, Jianhua4; Wen, Weijia1,2,3; Weijia Wen
Source PublicationJOURNAL OF NANOMATERIALS
2013
ISSN1687--4110
DOI10.1155/2013/864584
Volume2013Pages:864584
Indexed BySCI
Cooperation Status
SubtypeArticle
Department18
Funding Project1807
Contribution Rank待补充
WOS HeadingsScience & Technology ; Technology
Funding Organization3,6 ; 3,6 ; 3,6 ; 3,6
WOS SubjectNanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS Research AreaScience & Technology - Other Topics ; Materials Science
WOS KeywordDRUG-DELIVERY ; MICROCAPSULES ; FABRICATION ; MICRONEEDLES ; DESIGN
AbstractWe report a robust magnetic-membrane-based microfluidic platform for controllable chemical release. The magnetic membrane was prepared by mixing polydimethylsiloxane (PDMS) and carbonyl-iron nanoparticles together to obtain a flexible thin film. With combined, simultaneous regulation of magnetic stimulus and mechanical pumping, the desired chemical release rate can easily be realized. For example, the dose release experimental data was well fitted by a mathematical sigmoidal model, exhibiting a typical dose-response relationship, which shows promise in providing significant guidance for on-demand drug delivery. To test the platform's feasibility, our microfluidic device was employed in an experiment involving Escherichia coli culture under controlled antibiotic ciprofloxacin exposure, and the expected outcomes were successfully obtained. Our experimental results indicate that such a microfluidic device, with high accuracy and easy manipulation properties, can legitimately be characterized as active chemical release system.
Language英语
Funding Organization3,6 ; 3,6 ; 3,6 ; 3,6
URL查看原文
WOS IDWOS:000325321100001
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/119274
Collection中国科学院大连化学物理研究所
Corresponding AuthorWeijia Wen
Affiliation1.Hong Kong Univ Sci & Technol, Nanosci & Nanotechnol Program, Kowloon, Hong Kong, Peoples R China
2.Hong Kong Univ Sci & Technol, Dept Phys, Kowloon, Hong Kong, Peoples R China
3.Hong Kong Univ Sci & Technol, KAUST HKUST Joint Micro Nanofluid Lab, Kowloon, Hong Kong, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China
Recommended Citation
GB/T 7714
Wang, Xiang,Li, Shunbo,Wang, Limu,et al. Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles[J]. JOURNAL OF NANOMATERIALS,2013,2013:864584.
APA Wang, Xiang.,Li, Shunbo.,Wang, Limu.,Yi, Xin.,Hui, Yu Sanna.,...&Weijia Wen.(2013).Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles.JOURNAL OF NANOMATERIALS,2013,864584.
MLA Wang, Xiang,et al."Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles".JOURNAL OF NANOMATERIALS 2013(2013):864584.
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