DICP OpenIR
Subject Area物理化学
Recent advances in monolithic columns for protein and peptide separation by capillary liquid chromatography
Liang, Yu; Zhang, Lihua; Zhang, Yukui; Zhang LH(张丽华)
KeywordMonoliths Capillary Liquid Chromatography Proteins Peptides Separation
Source PublicationANALYTICAL AND BIOANALYTICAL CHEMISTRY
2013-03-01
DOI10.1007/s00216-012-6570-x
Volume405Issue:7Pages:2095-2106
Indexed BySCI
Cooperation Status
SubtypeReview
Department18
Funding Project1810
Contribution Rank待补充
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
Funding Organization1,1 ; 1,1 ; 1,1 ; 1,1
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS KeywordHYDROPHILIC INTERACTION CHROMATOGRAPHY ; POROUS POLYMER MONOLITHS ; ONE-POT APPROACH ; MASS-SPECTROMETRY ; SMALL MOLECULES ; HIGH-EFFICIENCY ; RADICAL POLYMERIZATION ; OCTADECYL METHACRYLATE ; GOLD NANOPARTICLES ; PROTEOMICS
AbstractCapillary liquid chromatography (cLC) has great potential for protein and peptide separation, with advantages of high efficiency, high resolution, low sample consumption, and high sensitivity when coupled with mass spectrometry. In recent years, monoliths have been widely used as the stationary phases for capillary columns, owing to easy preparation, high permeability, fast mass transfer, and low backpressure. This review summarizes recent advances (2007-2012) in monolithic columns for protein and peptide separation by cLC. After a brief introduction on the preparation of monolithic capillary columns, the emphasis of this review is focused on the recent application of such columns for protein and peptide separation by cLC. Furthermore, the challenges and potential hot points of monolithic capillary columns in the future are discussed.
Language英语
Funding Organization1,1 ; 1,1 ; 1,1 ; 1,1
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WOS IDWOS:000315043800002
Citation statistics
Cited Times:34[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/119334
Collection中国科学院大连化学物理研究所
Corresponding AuthorZhang LH(张丽华)
AffiliationChinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Liang, Yu,Zhang, Lihua,Zhang, Yukui,et al. Recent advances in monolithic columns for protein and peptide separation by capillary liquid chromatography[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2013,405(7):2095-2106.
APA Liang, Yu,Zhang, Lihua,Zhang, Yukui,&张丽华.(2013).Recent advances in monolithic columns for protein and peptide separation by capillary liquid chromatography.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,405(7),2095-2106.
MLA Liang, Yu,et al."Recent advances in monolithic columns for protein and peptide separation by capillary liquid chromatography".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 405.7(2013):2095-2106.
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