DICP OpenIR
Subject Area物理化学
Synthesis of molecularly imprinted polymer sorbents and application for the determination of aminoglycosides antibiotics in honey
Ji, Shunli1; Zhang, Feifang1; Luo, Xi1; Yang, Bingcheng1; Jin, Gaowa2; Yan, Jingyu2; Liang, Xinmiao1,2; Yang BC(杨丙成)
KeywordMolecularly Imprinted Polymer Hilic-ms/ms Aminoglycoside Antibiotics Solid Phase Extraction Honey Samples
Source PublicationJOURNAL OF CHROMATOGRAPHY A
2013-10-25
DOI10.1016/j.chroma.2013.08.072
Volume1313Pages:113-118
Indexed BySCI
Cooperation Status
SubtypeArticle
Department18
Funding Project1803
Contribution Rank待补充
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
Funding Organization2,5 ; 2,5 ; 2,5 ; 2,5
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS KeywordSOLID-PHASE MICROEXTRACTION ; CHROMATOGRAPHY/TANDEM MASS-SPECTROMETRY ; LIQUID-CHROMATOGRAPHY ; HYDROPHILIC INTERACTION ; EXTRACTION ; SAMPLES ; FLUOROQUINOLONES ; STREPTOMYCIN ; RECOGNITION ; SEPARATION
AbstractAminoglycoside antibiotic (AA)-selective molecularly imprinted polymer (MIP) sorbent was synthesized by polymerization of methacrylic acid and ethylene glycol dimethacrylate in the presence of streptomycin as template molecule. The MIP sorbent was in detail characterized and its performance was evaluated by selecting four model AAs including streptomycin, gentamicin, spectinomycin and dihydrostreptomycin. Relative to non-imprinted polymer (NIP), the MIPs exhibited much higher recognizable capacity and specificity to the AAs and negligible adsorption for non-AAs as well. In combination of hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS), the MIP sorbent-based solid phase extraction (SPE) was able to effectively determine the residue of four model AAs in honey samples with recovery ranging from 90% to 110%. The limit of detection (and the limit of quantitation) of streptomycin, gentamicin, spectinomycin and dihydrostreptomycin was 4.5 (15.0), 2.4 (8.0), 6.0 (20.0) and 1.8 (6.0) mu g/kg, respectively. Relative standard deviations of intraday and inter-day assay under three spiked levels were 4.4-12.0% and 6.8-14.6%, respectively. (c) 2013 Elsevier B.V. All rights reserved.
Language英语
Funding Organization2,5 ; 2,5 ; 2,5 ; 2,5
URL查看原文
WOS IDWOS:000325673200010
Citation statistics
Cited Times:31[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/119343
Collection中国科学院大连化学物理研究所
Corresponding AuthorYang BC(杨丙成)
Affiliation1.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Ji, Shunli,Zhang, Feifang,Luo, Xi,et al. Synthesis of molecularly imprinted polymer sorbents and application for the determination of aminoglycosides antibiotics in honey[J]. JOURNAL OF CHROMATOGRAPHY A,2013,1313:113-118.
APA Ji, Shunli.,Zhang, Feifang.,Luo, Xi.,Yang, Bingcheng.,Jin, Gaowa.,...&杨丙成.(2013).Synthesis of molecularly imprinted polymer sorbents and application for the determination of aminoglycosides antibiotics in honey.JOURNAL OF CHROMATOGRAPHY A,1313,113-118.
MLA Ji, Shunli,et al."Synthesis of molecularly imprinted polymer sorbents and application for the determination of aminoglycosides antibiotics in honey".JOURNAL OF CHROMATOGRAPHY A 1313(2013):113-118.
Files in This Item:
File Name/Size DocType Version Access License
2013IYV37KVjNz.PDF(1218KB) 开放获取CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Ji, Shunli]'s Articles
[Zhang, Feifang]'s Articles
[Luo, Xi]'s Articles
Baidu academic
Similar articles in Baidu academic
[Ji, Shunli]'s Articles
[Zhang, Feifang]'s Articles
[Luo, Xi]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Ji, Shunli]'s Articles
[Zhang, Feifang]'s Articles
[Luo, Xi]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.