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学科主题物理化学
Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots
Zhang, Wei1,2; He, Xi-Wen1,2; Yang, Ya-Qiong1,2; Li, Wen-You1,2; Zhang, Yu-Kui1,2,3; Li WY(李文友)
刊名JOURNAL OF MATERIALS CHEMISTRY B
2013
DOI10.1039/c2tb00022a
1期:3页:347-352
收录类别SCI
合作性质
文章类型Article
部门归属18
项目归属1810
产权排名待补充
WOS标题词Science & Technology ; Technology
资助者2,5 ; 2,5 ; 2,5 ; 2,5
类目[WOS]Materials Science, Biomaterials
研究领域[WOS]Materials Science
关键词[WOS]LECTIN AFFINITY ; ENRICHMENT ; CHROMATOGRAPHY ; GLYCOSYLATION ; PROTEINS
英文摘要In this work, aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots (APBA-coated QDs) were synthesized and applied to the selective capture and fluorescent quantification of glycoproteins. The as-prepared APBA-coated QDs, relying on the interaction between APBA and cis-diol containing structures, demonstrated excellent selectivity for the glycoproteins. Their high surface area and APBA-enriched silica matrixes give rise to faster binding kinetics and higher binding capacity for the glycoproteins, which further make them attractive for biomedical/chemical sensing applications. Based on the fluorescent properties of the particles, the as-prepared APBA-coated QDs were successfully applied to the fluorescence quantification of glycoproteins. The present study provides a facile strategy to fabricate functionalized fluorescent materials and is of great significance for isolation and detection of glycoproteins in proteomics.
语种英语
资助者2,5 ; 2,5 ; 2,5 ; 2,5
原文出处查看原文
WOS记录号WOS:000314787400011
引用统计
被引频次:20[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/119459
专题中国科学院大连化学物理研究所
通讯作者Li WY(李文友)
作者单位1.Nankai Univ, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China
2.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116011, Peoples R China
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Zhang, Wei,He, Xi-Wen,Yang, Ya-Qiong,et al. Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots[J]. JOURNAL OF MATERIALS CHEMISTRY B,2013,1(3):347-352.
APA Zhang, Wei,He, Xi-Wen,Yang, Ya-Qiong,Li, Wen-You,Zhang, Yu-Kui,&李文友.(2013).Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots.JOURNAL OF MATERIALS CHEMISTRY B,1(3),347-352.
MLA Zhang, Wei,et al."Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots".JOURNAL OF MATERIALS CHEMISTRY B 1.3(2013):347-352.
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