DICP OpenIR
Subject Area物理化学
The impact of the number of layers of a graphene nanopore on DNA translocation
Lv, Wenping1; Chen, Maodu2; Wu, Ren'an1; Wu RA(吴仁安)
Source PublicationSOFT MATTER
2013
DOI10.1039/c2sm26476e
Volume9Issue:3Pages:960-966
Indexed BySCI
Cooperation Status
SubtypeArticle
Department18
Funding Project18T1
Contribution Rank待补充
WOS HeadingsScience & Technology ; Physical Sciences ; Technology
Funding Organization1,1 ; 1,1 ; 1,1 ; 1,1
WOS SubjectChemistry, Physical ; Materials Science, Multidisciplinary ; Physics, Multidisciplinary ; Polymer Science
WOS Research AreaChemistry ; Materials Science ; Physics ; Polymer Science
WOS KeywordMOLECULAR-DYNAMICS ; SYNTHETIC NANOPORE ; NUCLEIC-ACIDS ; SIMULATION ; WATER ; CONDUCTANCE ; COMPLEXES ; MEMBRANE ; POLYMER ; SENSORS
AbstractGraphene nanopore based sensor devices have shown great potential for the detection of DNA. To understand the fundamental aspects of DNA translocation through a graphene nanopore, in this work, molecular dynamics (MD) simulations and potential of mean force (PMF) calculations were carried out to investigate the impact of the number of graphene layers of small nanopores (2-3 nm) on DNA translocation. It was observed that the ionic conductance was sensitive to the number of graphene layers of open-nanopores, and the probability of DNA translocation through graphene nanopores was related to the thickness of the graphene nanopores. MD simulations showed that DNA translocation time was most sensitive to the thickness of graphene nanopores of 2.4 nm aperture, and the observed free energy barrier of PMFs and the profile change revealed the increased retardation of DNA translocation through bilayer graphene nanopores as compared to that through monolayer graphene nanopores.
Language英语
Funding Organization1,1 ; 1,1 ; 1,1 ; 1,1
URL查看原文
WOS IDWOS:000312335500040
Citation statistics
Cited Times:34[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/119600
Collection中国科学院大连化学物理研究所
Corresponding AuthorWu RA(吴仁安)
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Dalian Univ Technol, Sch Phys & Optoelect Technol, Dalian 116024, Peoples R China
Recommended Citation
GB/T 7714
Lv, Wenping,Chen, Maodu,Wu, Ren'an,et al. The impact of the number of layers of a graphene nanopore on DNA translocation[J]. SOFT MATTER,2013,9(3):960-966.
APA Lv, Wenping,Chen, Maodu,Wu, Ren'an,&吴仁安.(2013).The impact of the number of layers of a graphene nanopore on DNA translocation.SOFT MATTER,9(3),960-966.
MLA Lv, Wenping,et al."The impact of the number of layers of a graphene nanopore on DNA translocation".SOFT MATTER 9.3(2013):960-966.
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