DICP OpenIR
Subject Area物理化学
Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza
Gao, Wei1,2; Sun, Hai-Xi3; Xiao, Hongbin4; Cui, Guanghong1; Hillwig, Matthew L.5; Jackson, Alana5; Wang, Xiao1; Shen, Ye1; Zhao, Nan4; Zhang, Liangxiao4; Wang, Xiu-Jie3; Peters, Reuben J.5; Huang, Luqi1; Xiu-Jie Wang; Reuben J Peters; Luqi Huang
Source PublicationBMC GENOMICS
2014-01-28
DOI10.1186/1471-2164-15-73
Volume15Issue:73Pages:1
Indexed BySCI
Cooperation Status
SubtypeArticle
Department18
Funding Project1804
Contribution Rank待补充
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Funding Organization4,3 ; 4,3 ; 4,3 ; 4,3
WOS SubjectBiotechnology & Applied Microbiology ; Genetics & Heredity
WOS Research AreaBiotechnology & Applied Microbiology ; Genetics & Heredity
WOS KeywordHAIRY-ROOT CULTURE ; ISOPRENOID BIOSYNTHESIS ; MASS-SPECTROMETRY ; GENE-EXPRESSION ; YEAST ELICITOR ; PATHWAYS ; RICE ; ENHANCEMENT ; METABOLISM ; ACTIVATION
AbstractBackground: Plant natural products have been co-opted for millennia by humans for various uses such as flavor, fragrances, and medicines. These compounds often are only produced in relatively low amounts and are difficult to chemically synthesize, limiting access. While elucidation of the underlying biosynthetic processes might help alleviate these issues (e. g., via metabolic engineering), investigation of this is hindered by the low levels of relevant gene expression and expansion of the corresponding enzymatic gene families. However, the often-inducible nature of such metabolic processes enables selection of those genes whose expression pattern indicates a role in production of the targeted natural product.
Language英语
Funding Organization4,3 ; 4,3 ; 4,3 ; 4,3
URL查看原文
WOS IDWOS:000331116500003
Citation statistics
Cited Times:70[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/119824
Collection中国科学院大连化学物理研究所
Corresponding AuthorXiu-Jie Wang; Reuben J Peters; Luqi Huang
Affiliation1.Chinese Acad Med Sci, Natl Resource Ctr Chinese Mat Med, Beijing 100700, Peoples R China
2.Capital Med Univ, Sch Tradit Chinese Med, Beijing 100069, Peoples R China
3.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing 100101, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
5.Iowa State Univ, Dept Biochem Biophys & Mol Biol, Ames, IA 50011 USA
Recommended Citation
GB/T 7714
Gao, Wei,Sun, Hai-Xi,Xiao, Hongbin,et al. Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza[J]. BMC GENOMICS,2014,15(73):1.
APA Gao, Wei.,Sun, Hai-Xi.,Xiao, Hongbin.,Cui, Guanghong.,Hillwig, Matthew L..,...&Luqi Huang.(2014).Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza.BMC GENOMICS,15(73),1.
MLA Gao, Wei,et al."Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza".BMC GENOMICS 15.73(2014):1.
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