中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Metabolite profile analysis of aconitine in rabbit stomach after oral administration by liquid chromatography/electrospray ionization/multiple- stage tandem mass spectrometry
作者: Sui, Zhigang1, 2;  Li, Na2;  Liu, Zhiqiang3;  Yan, Jun1;  Liu, Zhongying1
关键词: Aconitine ;  fragmentation pathway ;  LC/ESI/MSn ;  metabolites ;  stomach
刊名: XENOBIOTICA
发表日期: 2013-07-01
DOI: 10.3109/00498254.2012.753490
卷: 43, 期:7, 页:628-635
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Pharmacology & Pharmacy ;  Toxicology
研究领域[WOS]: Pharmacology & Pharmacy ;  Toxicology
英文摘要: 1. Aconitine (AC), an active and highly toxic constituent extracted from aconitum plants, is well known for its excellent effects against rheumatism and rheumatoid arthritis. The metabolism of AC in liver and intestine has been previously reported. However, little is known about the metabolism of AC in stomach. In this study, the metabolite profiling of AC in stomachs of rabbit and rat was performed by liquid chromatography/electrospray ionization/multiple-stage tandem mass spectrometry (LC/ESI/MSn), for the first time.
关键词[WOS]: HUMAN INTESTINAL BACTERIA ;  TISSUE DISTRIBUTION ;  MAIN METABOLITE ;  ALKALOIDS ;  RATS ;  BIOTRANSFORMATION
语种: 英语
WOS记录号: WOS:000319881000007
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/137560
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Jilin Univ, Coll Pharm, Changchun 130021, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China
3.Chinese Acad Sci, Chang Chun Inst Appl Chem, Changchun, Peoples R China

Recommended Citation:
Sui, Zhigang,Li, Na,Liu, Zhiqiang,et al. Metabolite profile analysis of aconitine in rabbit stomach after oral administration by liquid chromatography/electrospray ionization/multiple- stage tandem mass spectrometry[J]. XENOBIOTICA,2013,43(7):628-635.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Sui, Zhigang]'s Articles
 [Li, Na]'s Articles
 [Liu, Zhiqiang]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Sui, Zhigang]‘s Articles
 [Li, Na]‘s Articles
 [Liu, Zhiqiang]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace