中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Study of the peak variance in isocratic and gradient liquid chromatography using the transport model
作者: Hao, Weiqiang1;  Di, Bin2;  Chen, Qiang1;  Wang, Junde3;  Yang, Yongbin1;  Sun, Xiaoli1
关键词: Gradient elution ;  Liquid chromatography ;  Transport model ;  Plate height
刊名: JOURNAL OF CHROMATOGRAPHY A
发表日期: 2013-06-21
DOI: 10.1016/j.chroma.2013.04.044
卷: 1295, 页:67-81
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry
英文摘要: The expressions accounting for the peak variance in isocratic and gradient liquid chromatography is derived from the transport model. In mathematical treatments, the dwelling time is taken into account, and the type of solvent strength, gradient profile and the variation of plate height (H) with mobile phase composition (phi) is not specified. By applying a coordinate transformation, the transport model is solved by using the Laplace transform approach. A plate height equation that is suited for both isocratic and gradient elution is obtained. Based on this equation, the plate height equations for any combination of stepwise and linear gradients are derived. These equations will be algebraic when the solvent strength is linear and the H-phi plot is parabolic. The plate height equations for single stepwise, single linear and the ladder-like gradients are also given. (C) 2013 Elsevier B.V. All rights reserved.
关键词[WOS]: MASS-TRANSFER KINETICS ;  ELUTION CHROMATOGRAPHY ;  ION-EXCHANGE ;  COMPRESSION FACTOR ;  FRONTAL ANALYSIS ;  LINEAR GRADIENT ;  IDEAL MODEL ;  PHASE ;  SEPARATIONS ;  PROTEINS
语种: 英语
WOS记录号: WOS:000320294000007
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/137666
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Nanjing Univ, High Tech Res Inst, Changzhou 213164, Peoples R China
2.China Pharmaceut Univ, Dept Pharmaceut Anal, Nanjing 210009, Jiangsu, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

Recommended Citation:
Hao, Weiqiang,Di, Bin,Chen, Qiang,et al. Study of the peak variance in isocratic and gradient liquid chromatography using the transport model[J]. JOURNAL OF CHROMATOGRAPHY A,2013,1295:67-81.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Hao, Weiqiang]'s Articles
 [Di, Bin]'s Articles
 [Chen, Qiang]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Hao, Weiqiang]‘s Articles
 [Di, Bin]‘s Articles
 [Chen, Qiang]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace