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Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production
Zhou, Yongjin J.1; Yang, Wei1; Wang, Lei1; Zhu, Zhiwei1; Zhang, Sufang1,2; Zhao, Zongbao K.1,2,3
关键词Cofactor Engineering Nad(h) Level Nad(+) Transporter Escherichia Coli Dihydroxyacetone Whole-cell Biocatalysis
刊名MICROBIAL CELL FACTORIES
2013-11-09
DOI10.1186/1475-2859-12-103
12
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biotechnology & Applied Microbiology
研究领域[WOS]Biotechnology & Applied Microbiology
关键词[WOS]GLUCONOBACTER-OXYDANS ; GLYCEROL DEHYDROGENASE ; GLUCOSE-DEHYDROGENASE ; GENE ; MUTANT ; NADH ; 1,3-DIHYDROXYACETONE ; BIOTRANSFORMATION ; REGENERATION ; ENHANCEMENT
英文摘要Background: Whole-cell redox biocatalysis has been intensively explored for the production of valuable compounds because excellent selectivity is routinely achieved. Although the cellular cofactor level, redox state and the corresponding enzymatic activity are expected to have major effects on the performance of the biocatalysts, our ability remains limited to predict the outcome upon variation of those factors as well as the relationship among them.
语种英语
WOS记录号WOS:000328948200001
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文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/137741
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China
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GB/T 7714
Zhou, Yongjin J.,Yang, Wei,Wang, Lei,et al. Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production[J]. MICROBIAL CELL FACTORIES,2013,12.
APA Zhou, Yongjin J.,Yang, Wei,Wang, Lei,Zhu, Zhiwei,Zhang, Sufang,&Zhao, Zongbao K..(2013).Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production.MICROBIAL CELL FACTORIES,12.
MLA Zhou, Yongjin J.,et al."Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production".MICROBIAL CELL FACTORIES 12(2013).
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