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Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production
Zhou, Yongjin J.1; Yang, Wei1; Wang, Lei1; Zhu, Zhiwei1; Zhang, Sufang1,2; Zhao, Zongbao K.1,2,3
KeywordCofactor Engineering Nad(h) Level Nad(+) Transporter Escherichia Coli Dihydroxyacetone Whole-cell Biocatalysis
Source PublicationMICROBIAL CELL FACTORIES
2013-11-09
DOI10.1186/1475-2859-12-103
Volume12
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS SubjectBiotechnology & Applied Microbiology
WOS Research AreaBiotechnology & Applied Microbiology
WOS KeywordGLUCONOBACTER-OXYDANS ; GLYCEROL DEHYDROGENASE ; GLUCOSE-DEHYDROGENASE ; GENE ; MUTANT ; NADH ; 1,3-DIHYDROXYACETONE ; BIOTRANSFORMATION ; REGENERATION ; ENHANCEMENT
AbstractBackground: Whole-cell redox biocatalysis has been intensively explored for the production of valuable compounds because excellent selectivity is routinely achieved. Although the cellular cofactor level, redox state and the corresponding enzymatic activity are expected to have major effects on the performance of the biocatalysts, our ability remains limited to predict the outcome upon variation of those factors as well as the relationship among them.
Language英语
WOS IDWOS:000328948200001
Citation statistics
Cited Times:26[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/137741
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Zhou, Yongjin J.,Yang, Wei,Wang, Lei,et al. Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production[J]. MICROBIAL CELL FACTORIES,2013,12.
APA Zhou, Yongjin J.,Yang, Wei,Wang, Lei,Zhu, Zhiwei,Zhang, Sufang,&Zhao, Zongbao K..(2013).Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production.MICROBIAL CELL FACTORIES,12.
MLA Zhou, Yongjin J.,et al."Engineering NAD(+) availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production".MICROBIAL CELL FACTORIES 12(2013).
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