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题名: A rapid, straightforward, and print house compatible mass fabrication method for integrating 3D paper-based microfluidics
作者: Xiao, Liangpin1, 2;  Liu, Xianming1;  Zhong, Runtao1;  Zhang, Kaiqing3;  Zhang, Xiaodi3;  Zhou, Xiaomian4;  Lin, Bingcheng1;  Du, Yuguang1
关键词: 3D paper-based microfluidics ;  Nitrite colorimetric assay ;  Print house compatible mass fabrication ;  Wax-printing
刊名: ELECTROPHORESIS
发表日期: 2013-11-01
DOI: 10.1002/elps.201300198
卷: 34, 期:20-21, 页:3003-3007
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry
英文摘要: Three-dimensional (3D) paper-based microfluidics, which is featured with high performance and speedy determination, promise to carry out multistep sample pretreatment and orderly chemical reaction, which have been used for medical diagnosis, cell culture, environment determination, and so on with broad market prospect. However, there are some drawbacks in the existing fabrication methods for 3D paper-based microfluidics, such as, cumbersome and time-consuming device assembly; expensive and difficult process for manufacture; contamination caused by organic reagents from their fabrication process. Here, we present a simple printing-bookbinding method for mass fabricating 3D paper-based microfluidics. This approach involves two main steps: (i) wax-printing, (ii) bookbinding. We tested the delivery capability, diffusion rate, homogeneity and demonstrated the applicability of the device to chemical analysis by nitrite colorimetric assays. The described method is rapid (<30 s), cheap, easy to manipulate, and compatible with the flat stitching method that is common in a print house, making itself an ideal scheme for large-scale production of 3D paper-based microfluidics.
关键词[WOS]: IMMUNODEVICE ;  DEVICE ;  IMMUNOASSAY ;  TAPE
语种: 英语
WOS记录号: WOS:000330127500008
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/137886
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Res Ctr Lab Chip, Dalian, Peoples R China
2.Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing, Peoples R China
3.Bioman Technol Co Ltd, Guangzhou, Guangdong, Peoples R China
4.Guangzhou Med Univ, Affiliated Hosp, Guangzhou Municipal Peoples Hosp 1, Dept Lab Med, Guangzhou, Guangdong, Peoples R China

Recommended Citation:
Xiao, Liangpin,Liu, Xianming,Zhong, Runtao,et al. A rapid, straightforward, and print house compatible mass fabrication method for integrating 3D paper-based microfluidics[J]. ELECTROPHORESIS,2013,34(20-21):3003-3007.
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