中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: A "one step" approach for preparation of an octadecyl-silica hybrid monolithic column via a non-hydrolytic sol-gel (NHSG) method
作者: Zhang, Zhenbin1, 2;  Wang, Fangjun1;  Dong, Jing1;  Lin, Hui1, 2;  Ou, Junjie1;  Zou, Hanfa1
刊名: RSC ADVANCES
发表日期: 2013
DOI: 10.1039/c3ra42003e
卷: 3, 期:44, 页:22160-22167
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: An octadecyl (C18)-silica hybrid monolithic column was prepared via a "one step", non-hydrolytic sol-gel (NHSG) method for capillary liquid chromatography (cLC). The effects of various preparation conditions (e.g., polycondensation temperature, alkyl alcohols and crosslinkers) on the morphologies and column efficiencies were studied in detail. Under the optimized conditions, uniform monolithic matrices were obtained, and the minimum plate height for benzene was 11.5 mu m, corresponding to ca. 87 000 theoretical plates per meter (N m(-1)). Baseline-separations of phenolic compounds, benzonic acids and anilines on the prepared C18-silica hybrid monolithic column were achieved by cLC with isocratic elution and showed high efficiency and satisfactory reproducibility. In addition, 16 priority pollutant polycyclic aromatic hydrocarbons (PAHs) and 6 proteins mixture were also well separated on the C18-silica hybrid monolithic column with gradient elution by cLC. Moreover, the prepared hybrid monolithic column was also applied to the analysis of tryptic digests of bovine serum albumin (BSA) by cLC tandem mass spectrometry (cLC-MS/MS), and the results showed that the separation performance was close to that of the C18-particulates packed capillary column, demonstrating its potential in proteome analysis.
关键词[WOS]: PERFORMANCE LIQUID-CHROMATOGRAPHY ;  IONIZATION MASS-SPECTROMETRY ;  CAPILLARY ELECTROCHROMATOGRAPHY ;  STATIONARY PHASES ;  CHIRAL SEPARATION ;  NANOPARTICLES ;  FABRICATION ;  ROUTES ;  FLOW
语种: 英语
WOS记录号: WOS:000326056600144
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/137909
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Sch Chinese Acad Sci, Beijing 100039, Peoples R China

Recommended Citation:
Zhang, Zhenbin,Wang, Fangjun,Dong, Jing,et al. A "one step" approach for preparation of an octadecyl-silica hybrid monolithic column via a non-hydrolytic sol-gel (NHSG) method[J]. RSC ADVANCES,2013,3(44):22160-22167.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Zhang, Zhenbin]'s Articles
 [Wang, Fangjun]'s Articles
 [Dong, Jing]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Zhang, Zhenbin]‘s Articles
 [Wang, Fangjun]‘s Articles
 [Dong, Jing]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace