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Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-oxindoles via Bronsted Acid Catalyzed sp(3) C-H Functionalization
Niu, Rui1,2,3; Xiao, Jian1; Liang, Tao1; Li, Xingwei1
Source PublicationORGANIC LETTERS
2012-02-03
DOI10.1021/ol2030982
Volume14Issue:3Pages:676-679
Indexed BySCI ; IC ; CCR
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Organic
WOS Research AreaChemistry
WOS KeywordBAYLIS-HILLMAN REACTION ; ENANTIOSELECTIVE SYNTHESIS ; ASYMMETRIC CATALYSIS ; ISATIN DERIVATIVES ; BOND ACTIVATION ; 3-HYDROXYOXINDOLE DERIVATIVES ; ARYLBORONIC ACIDS ; ALPHA-KETOAMIDES ; ALDOL REACTION ; OXINDOLES
AbstractBronsted acid catalyzed functionalization of sp(3) C-H bonds in 2-methyl azaarenes has been achieved in the reaction with isatins. This method provides facile synthesis of biologically important azaarene-substituted 3-hydroxy-2-oxindoles in one step in moderate to good yields.
Language英语
WOS IDWOS:000300458200003
Citation statistics
Cited Times:110[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/138003
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Ocean Univ China, Coll Environm Sci & Engn, Qingdao 266100, Peoples R China
3.Ocean Univ China, Minist Educ, Key Lab Marine Environm & Ecol, Qingdao 266100, Peoples R China
Recommended Citation
GB/T 7714
Niu, Rui,Xiao, Jian,Liang, Tao,et al. Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-oxindoles via Bronsted Acid Catalyzed sp(3) C-H Functionalization[J]. ORGANIC LETTERS,2012,14(3):676-679.
APA Niu, Rui,Xiao, Jian,Liang, Tao,&Li, Xingwei.(2012).Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-oxindoles via Bronsted Acid Catalyzed sp(3) C-H Functionalization.ORGANIC LETTERS,14(3),676-679.
MLA Niu, Rui,et al."Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-oxindoles via Bronsted Acid Catalyzed sp(3) C-H Functionalization".ORGANIC LETTERS 14.3(2012):676-679.
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